host restriction in the productive cycle of avian polyomavirus budgerigar fledgling disease virus type 3 depends on a single amino acid change in the common region of structural proteins vp2/vp3.the three avian polyomaviruses budgerigar fledgling disease virus types 1 to 3 (bfdv-1 to -3) contain genomes of identical size, 4981 bp. with differences of up to only 15 bp between the three genomes, these viruses show distinct tropism for cultured cells of various avian species: infection of chicken embryo (ce) cells with bfdv-1 and -2 results in virus propagation, whereas bfdv-3 is not replicated; all three viruses replicate, with different efficiencies, in infected muscovy duck cells. trans ...19948077924
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