| clinical diagnosis and treatment of epidermal chytridiomycosis in african clawed frogs (xenopus tropicalis). | an investigation was conducted to determine the cause of morbidity and mortality in a collection of 55 adult male xenopus (silurana) tropicalis at the university of california, berkeley. more than 80% of affected frogs died during the epizootic. all frogs were anorectic and lethargic, had dark pigmentation and excess skin sloughing, and lacked a slime layer. histologic examination revealed severe hyperplastic and spongiotic dermatitis associated with colonization of the stratum corneum by large ... | 2002 | 12102573 |
| only skin deep: shared genetic response to the deadly chytrid fungus in susceptible frog species. | amphibian populations around the world are threatened by an emerging infectious pathogen, the chytrid fungus batrachochytrium dendrobatidis (bd). how can a fungal skin infection kill such a broad range of amphibian hosts? and do different host species have a similar response to bd infection? here, we use a genomics approach to understand the genetic response of multiple susceptible frog species to bd infection. we characterize the transcriptomes of two closely related endangered frog species (ra ... | 2012 | 22332717 |
| expression profiling the temperature-dependent amphibian response to infection by batrachochytrium dendrobatidis. | amphibians are experiencing a panzootic of unprecedented proportions caused by the emergence of batrachochytrium dendrobatidis (bd). however, all species are not equally at risk of infection, and risk is further modified by environmental variables, specifically temperature. in order to understand how, and when, hosts mount a response to bd we analysed infection dynamics and patterns of gene expression in the model amphibian species silurana (xenopus) tropicalis. mathematical modelling of infecti ... | 2009 | 20027316 |
| genome-wide transcriptional response of silurana (xenopus) tropicalis to infection with the deadly chytrid fungus. | emerging infectious diseases are of great concern for both wildlife and humans. several highly virulent fungal pathogens have recently been discovered in natural populations, highlighting the need for a better understanding of fungal-vertebrate host-pathogen interactions. because most fungal pathogens are not fatal in the absence of other predisposing conditions, host-pathogen dynamics for deadly fungal pathogens are of particular interest. the chytrid fungus batrachochytrium dendrobatidis (here ... | 2009 | 19701481 |