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characterization of a ranavirus inhibitor of the antiviral protein kinase pkr.ranaviruses (family iridoviridae) are important pathogens of lower vertebrates. however, little is known about how they circumvent the immune response of their hosts. many ranaviruses contain a predicted protein, designated vif2a, which shows homology with the eukaryotic translation initiation factor 2a. in analogy to distantly related proteins found in poxviruses vif2a might act as an inhibitor of the antiviral protein kinase pkr.201121418572
rana catesbeiana virus z (rcv-z): a novel pathogenic ranavirus.a virus, designated rana catesbeiana virus z (rcv-z), was isolated from the visceral tissue of moribund tadpoles of the north american bullfrog rana catesbeiana. sds-page (sodium dodecyl sulfate polyacrylamide gel electrophoresis) analysis of viral proteins and sequence analysis of the amino terminal end of the major capsid protein showed that rcv-z was similar to frog virus 3 (fv3) and other ranaviruses isolated from anurans and fish. however, analysis of restriction fragment profiles following ...200617240747
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