genetic diversity between and within the arenavirus species indigenous to western venezuela.the results of analyses of z, rna-dependent rna polymerase, glycoprotein precursor, and nucleocapsid protein gene sequence data suggested that guanarito virus was the most common cause of venezuelan hemorrhagic fever in a 7-year period in the 1990s and that the evolution of pirital virus in association with sigmodon alstoni (alston's cotton rat) has occurred at a significantly higher rate than the evolution of guanarito virus in association with zygodontomys brevicauda (short-tailed cane mouse) ...200818586298
transmission of guanarito and pirital viruses among wild rodents, venezuela.samples from rodents captured on a farm in venezuela in february 1997 were tested for arenavirus, antibody against guanarito virus (gtov), and antibody against pirital virus (pirv). thirty-one (48.4%) of 64 short-tailed cane mice (zygodontomys brevicauda) were infected with gtov, 1 alston's cotton rat (sigmodon alstoni) was infected with gtov, and 36 (64.3%) of 56 other alston's cotton rats were infected with pirv. the results of analyses of field and laboratory data suggested that horizontal tr ...201122172205
natural rodent host associations of guanarito and pirital viruses (family arenaviridae) in central venezuela.the objective of this study was to elucidate the natural rodent host relationships of guanarito and pirital viruses (family arenaviridae) in the plains of central venezuela. ninety-two arenavirus isolates from 607 animals, representing 10 different rodent species, were characterized to the level of serotype. the 92 isolates comprised 19 guanarito virus strains and 73 pirital virus strains. the 19 guanarito virus isolates were from zygodontomys brevicauda; 72 (98.6%) of the 73 pirital virus isola ...199910463688
isolation and characterization of pirital virus, a newly discovered south american arenavirus.specific rodent species are principal hosts for each of the well-characterized members of the virus family arenaviridae. guanarito virus (arenaviridae) is the etiologic agent of venezuelan hemorrhagic fever. a previous study on the epidemiology of venezuelan hemorrhagic fever revealed extensive arenavirus infection (presumed to be caused by guanarito virus) in two rodent species. sigmodon alstoni and zygodontomys brevicauda, collected from the region of venezuela in which the disease is endemic. ...19979180606
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