eilat virus, a unique alphavirus with host range restricted to insects by rna replication.most alphaviruses and many other arboviruses are mosquito-borne and exhibit a broad host range, infecting many different vertebrates including birds, rodents, equids, humans, and nonhuman primates. consequently, they can be propagated in most vertebrate and insect cell cultures. this ability of arboviruses to infect arthropods and vertebrates is usually essential for their maintenance in nature. however, several flaviviruses have recently been described that infect mosquitoes but not vertebrates ...201222908261
eilat virus displays a narrow mosquito vector range.most alphaviruses are arthropod-borne and utilize mosquitoes as vectors for transmission to susceptible vertebrate hosts. this ability to infect both mosquitoes and vertebrates is essential for maintenance of most alphaviruses in nature. a recently characterized alphavirus, eilat virus (eilv), isolated from a pool of anopheles coustani s.i. is unable to replicate in vertebrate cell lines. the eilv host range restriction occurs at both attachment/entry as well as genomic rna replication levels. h ...201425515341
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