Publications

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host and viral traits predict zoonotic spillover from mammals.the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ...201728636590
epidemiology of bat rabies in germany.rabies in european bats was first reported in germany in 1954. in concordance with denmark and the netherlands, germany has reported one of the highest numbers (n = 187) of european bat lyssavirus (eblv)-positive cases in bats in europe so far (1954-2005). a combined descriptive epidemiological and phylogenetic analysis on bat rabies and prevailing eblvs is presented, comprising the past 50 years. so far, only the two lineages of eblv-1 (genotype 5), a and b, have been detected. although only 50 ...200717066249
seroprevalence dynamics of european bat lyssavirus type 1 in a multispecies bat colony.we report an active surveillance study of the occurrence of specific antibodies to european bat lyssavirus type 1 (eblv-1) in bat species, scarcely studied hitherto, that share the same refuge. from 2004 to 2012, 406 sera were obtained from nine bat species. blood samples were subjected to a modified fluorescent antibody virus neutralization test to determine the antibody titer. eblv-1-neutralizing antibodies were detected in six of the nine species analyzed (pipistrellus pipistrellus, p. kuhlii ...201425192547
enhanced passive bat rabies surveillance in indigenous bat species from germany--a retrospective study.in germany, rabies in bats is a notifiable zoonotic disease, which is caused by european bat lyssaviruses type 1 and 2 (eblv-1 and 2), and the recently discovered new lyssavirus species bokeloh bat lyssavirus (bblv). as the understanding of bat rabies in insectivorous bat species is limited, in addition to routine bat rabies diagnosis, an enhanced passive surveillance study, i.e. the retrospective investigation of dead bats that had not been tested for rabies, was initiated in 1998 to study the ...201424784117
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