Publications

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antimycobacterial, antiprotozoal and cytotoxic potential of twenty-one brown algae (phaeophyceae) from british and irish waters.in the continuation of our research on seaweeds, crude extracts of 21 brown algae collected from the south coast of england and the west coast of ireland were screened for in vitro trypanocidal, leishmanicidal and antimycobacterial activities. mammalian stages of a small set of parasitic protozoa; i.e. trypanosoma brucei rhodesiense, t. cruzi and leishmania donovani, and the tubercle bacillus mycobacterium tuberculosis were used as test organisms. the extracts were also evaluated for selectivity ...201020564461
antiprotozoal, antimycobacterial and cytotoxic potential of twenty-three british and irish red algae.as part of our continuing research on seaweeds, we have screened the crude extracts of 23 red marine algae collected from england and ireland. the clinically important blood-stage life forms of trypanosoma brucei rhodesiense, t. cruzi, leishmania donovani and mycobacterium tuberculosis were used as test organisms in the in vitro assays. the selectivity of the extracts was determined by using mammalian skeletal myoblast (l6) cells. all algal extracts showed activity against t. brucei rhodesiense, ...201020077438
antiprotozoal, antitubercular and cytotoxic potential of cyanobacterial (blue-green algal) extracts from ireland.cyanobacteria (= blue-green algae) are prolific producers of structurally distinct and biologically active metabolites. in the continuation of our search for new sources of anti-infective natural products, we have assessed the in vitro antiprotozoal (plasmodium falciparum, trypanosoma brucei rhodesiense, t. cruzi, leishmania donovani) and antitubercular (mycobacterium tuberculosis) potential of samples of two terrestrial cyanobacteria, nostoc commune (collected when desiccated and wet) and rivul ...201121615033
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