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phe362tyr in ache: a major factor responsible for azamethiphos resistance in lepeophtheirus salmonis in norway.organophosphates (op) are one of the major treatments used against the salmon louse (lepeophtherius salmonis) in norwegian salmonid aquaculture. the use of op since the late 1970s has resulted in widespread resistant parasites. recently, we reported a single mutation (phe362tyr) in acetylcholinesterase (ache) as the major mechanism behind resistance in salmon louse towards op. the present study was carried out to validate this mechanism at the field level. a total of 6658 salmon louse samples we ...201626882536
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