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differential induction of cellular detachment by envelope glycoproteins of marburg and ebola (zaire) viruses.human infection by marburg (mbg) or ebola (ebo) virus is associated with fatal haemorrhagic fevers. while these filoviruses may both incite disease as a result of explosive virus replication, we hypothesized that expression of individual viral gene products, such as the envelope glycoprotein (gp), may directly alter target cells and contribute to pathogenesis. we found that expression of ebo gp in 293t cells caused significant levels of cellular detachment in the absence of cell death or virus r ...200010950971
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