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a baculovirus-expressed fusion protein containing the antibody-binding domain of protein a and insect luciferase.a fusion construct encoding two antibody-binding sites of protein a from staphylococcus aureus and click beetle, pyrophorus plagiophthalamus, luciferase (lucgr) was designed and expressed using the baculovirus system. the construct was inserted under the transcriptional regulation of the polyhedrin gene promoter of the autographa californica nuclear polyhedrosis virus (acnpv) and expressed in the insect spodoperta frugiperda cell line during viral infection. the properties of the resultant chime ...19938512706
baculovirus treatment fully protects mice against a lethal challenge of fmdv.foot-and-mouth disease virus (fmdv) causes a highly contagious and economically devastating disease that affects cattle, swine, goat and sheep among others. fmdv is able to overcome the initial host innate immune response by inhibiting the induction of antiviral molecules at both the transcriptional and the translational levels. it has been demonstrated that fmdv a/arg/2001 causes the death of adult c57bl/6 mice within 72h. we evaluated the capacity of autographa californica nuclear polyhedrosis ...201020580746
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