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bovine leukemia virus, a versatile agent with various pathogenic effects in various animal species.the bovine leukemia virus is the etiological agent of a chronic lymphatic leukemia in cows, sheep, and goats. the same virus seems to induce a kind of wasting disease in experimentally infected rabbits. antibodies to highly purified bovine leukemia viral mr 51,000 glycoprotein and mr 24,000 protein cross-react with human t-lymphotropic virus iii/lymphadenopathy-associated virus antigens present in cultured lymphocytes of african patients suffering from acquired immune deficiency syndrome. bovine ...19852410107
transmission of bovine leukemia virus by tabanus fuscicostatus.bovine leukemia virus (blv) was transmitted by horse flies, tabanus fuscicostatus, from a cow with a lymphocyte count of 31,500/mm3 to goats and dairy calves. as few as 10 and 20 flies transmitted blv to goats and calves respectively, but the minimal number of flies required to transmit the infection was not established. groups of 150 and 100 t fuscicostatus transmitted blv to beef calves from a cow with a lymphocyte count of 14,600/mm3. these results support a role for horse flies in the horizo ...19892552874
bovine leukaemia: facts and hypotheses derived from the study of an infectious cancer.bovine leukaemia virus (blv) is the etiological agent of chronic lymphatic leukaemia/lymphoma in cows, sheep and goats. infection without neoplastic transformation was also obtained in pigs, rhesus monkeys, chimpanzees, rabbits and observed in capybaras and water-buffaloes. structurally and functionally, blv is a relative of human t lymphotropic viruses 1 and 2 (htlv-i and htlv-ii) in humans, htlv-i induces a t-cell leukaemia and its type 2 counterpart has been found in dermatopathic lymphadenop ...19882847391
bovine leukemia: facts and hypotheses derived from the study of an infectious cancer.bovine leukemia virus is the etiological agent of a chronic lymphatic leukemia/lymphoma in cows, sheep, and goats. infection without neoplastic transformation also was obtained in pigs, rhesus monkeys, chimpanzees, and rabbits, and was observed in capybaras and water buffaloes. structurally and functionally, blv is a relative of the human t lymphotropic viruses (htlv-i and htlv-ii). htlv-i induces in humans a t cell leukemia, and its type ii counterpart has been found in dermatopathic lymphadeno ...19882847501
mechanical transmission of bovine leukemia virus by horse flies (diptera: tabanidae). 19882848127
bovine leukaemia: facts and hypotheses derived from the study of an infectious cancer.bovine leukaemia virus (blv) is the aetiological agent of a chronic lymphatic leukaemia/lymphoma in cows, sheep and goats. infection without neoplastic transformation has also been demonstrated in pigs, rhesus monkeys, chimpanzees and rabbits and observed in capybaras and water buffaloes. structurally and functionally, blv is a relative of human t lymphotropic viruses 1 and 2 (htlv-i and htlv-ii) since all three viruses show clear-cut sequence homologies. the pathology of the blv-induced disease ...19872891439
bovine leukaemia virus and enzootic bovine leukosis.infection of bovines with bovine leukaemia virus (blv) manifests itself in either of two ways: 30-70% of carriers develop persistent lymphocytosis (pl), with the viral genome integrated at a large number of different sites in the dna of the affected b-lymphocytes, without causing any chromosomal abnormalities. only 0,1-10% of carriers develop lymphoid tumours, which also consist of b-lymphocytes. in contrast to pl, however, they are of mono- or oligoclonal origin in terms of the integration site ...19853003647
experimental transmission of enzootic bovine leukosis to cattle, sheep and goats: infectious doses of blood and incubation period of the disease.a group of 49 blv-free recipient animals (24 cattle, 15 sheep and 10 goats) were inoculated intradermally with serial dilutions of blood collected on two blv-positive donor cows. one donor had a high lymphocytosis and high antibody titers to gpblv antigens; these two parameters were low for the second donor. the number of lymphocytes which induced blv infection in recipient animals varied widely with the donor. the high infectivity of a donor seemed to be correlated with high lymphocytosis and h ...19873031388
[genetic transformation of somatic cells. xiv. expression of gene coding for the human hepatitis b virus surface antigen in mammalian cells].a set of recombinant plasmids with a gene encoding surface antigen of hepatitis b virus (hbsag) is constructed. the plasmids were transfected by deae-dextran method into different lines of cultured cells and transient expression of the hbsag gene was studied. the results indicate that: transcriptional enhancer of hepatitis b virus situated downstream from hbsag gene is active in green monkey kidney cells (cvi), promoter of 5 ltr of bovine leukemia virus is trans-activated in the goat or calf cel ...19873603707
experimental infection of sheep and goat with bovine leukemia virus: localization of proviral information on the target cells.bovine leukemia virus (blv) proviral integration was studied in the dna from circulating leucocytes or tumor cells of sheep and goats experimentally infected with blv. southern blot analysis of infected cell dna for blv proviral sequences indicate that: (1) the provirus may be found as unintegrated molecules in the circulating leucocytes of infected sheep; (2) the provirus is integrated at many sites in the genome of the leucocytes of infected goats and occasionally in infected sheep; (3) the pr ...19846096636
experimental cross-transmissions of bovine leukemia virus (blv) between several animal species. 19816263020
goat lymphosarcoma from bovine leukemia virus.a goat given inoculations of sheep lymphocytes from cultures that produced bovine leukemia virus (blv) died 8 years later with lymphosarcoma. the tumors were located in various lymph nodes, the mesentery, omentum, body wall, and retrobulbar tissues. the blv had been cultured from lymphocytes during the first year after the goat's infection, and persisting blv antibodies could be demonstrated when the animal was 7.5 years old. blv provirus was identified by molecular hybridization in the dna of t ...19816268881
experiments with cloned complete tumor-derived bovine leukemia virus information prove that the virus is totally exogenous to its target animal species.taking advantage of the existence of a unique saci restriction site in the long terminal repeats of the integrated bovine leukemia virus proviral dna isolated from a bovine tumor, the total viral information (about 9.2 kilobases) was cloned in the lambdoid vector lambda wes. lambda b. use of this cloned bovine leukemia virus dna allowed us, for the first time, to definitely rule out the existence of any endogenous bovine leukemia virus sequence in the bovine, ovine, caprine, murine, feline, chic ...19816275107
ultrastructural comparison of oncovirinae (type c), spumavirinae, and lentivirinae: three subfamilies of retroviridae found in farm animals.the successive steps of maturation of seven retroviruses from five species of farm animals and one retrovirus from a mouse were compared in cell cultures. the viruses included three type c oncoviruses, one spumavirus, and three lentiviruses. although members of the 3 subfamilies shared some gross morphologic features such as budding on plasma membranes, core, and surface projections, differences were noted in the ultrastructural detail of these features. type c oncoviruses did not show any struc ...19846325793
prevalence of bovine herpesvirus-1, bovine viral diarrhea, parainfluenza-3, goat respiratory syncytial, bovine leukemia, and bluetongue viral antibodies in sheep.sera from healthy sheep were collected in january and march 1982 from flocks of sheep located in southwestern and southeastern louisiana. these sera were tested for bovine herpesvirus-1 (bhv-1), bovine viral diarrhea virus (bvdv), parainfluenza-3 (pi-3) virus, and goat respiratory syncytial virus (grsv) antibodies by microtitration virus-neutralization test. the sera were tested also for bovine leukemia virus (blv) and bluetongue virus (btv) antibodies by immunodiffusion tests. the number of flo ...19846329044
chromosomal localization of the blv receptor candidate gene in cattle, sheep, and goat.the blv receptor candidate gene has been localized precisely on cattle, goat, and sheep chromosomes using nonradioactive in situ hybridization and simultaneous fluorescent r-banding. the probe, a whole plasmid containing a 2.3-kb bovine cdna fragment encoding part of this gene, was nick-translated in the presence of biotin-11-dutp. it hybridized on band q15 of cattle chromosome 7, goat chromosome 7, and sheep chromosome 5, thus confirming the homoeology based on banding patterns among the chromo ...19957835086
localization of mouse homolog of the bovine leukemia virus receptor gene on mouse chromosome 10. 19968703134
food animal and poultry retroviruses and human health.in summary, studies reported to date have largely failed to demonstrate human infection with animal and poultry retroviruses or an association between human diseases and these viruses. a number of studies, most of them serologic, have attempted to demonstrate human infection with these viruses. the lack of antibodies in apparently exposed groups of persons suggests an absence of infection. however, another possible explanation is that humans may be immunologically unresponsive to infection with ...19979071753
livestock production and animal health in sicily, italy.in sicily, as in other mediterranean areas, livestock represents one of the most important resources for the island economy. this sector involves more than 16,000 farms of cattle and 10,000 farms of sheep and goats (respectively 6% and 15% of national production) which are actually increasing their number. most livestock in sicily is owned by small holders and pastoralists. regional production of milk feeds some industries, which involve a large and increasing occupational area. due to its pecul ...199911071536
serological survey for potential disease agents of free-ranging cervids in six selected national parks from germany.a total of 164 blood samples, collected from free-ranging red deer (cervus elaphus), roe deer (capreolus capreolus) and fallow deer (dama dama) in six german national parks (np) between 2000 and 2002, were assayed for antibodies against nine viral disease agents. antibodies were only detected against the alpha-herpesviruses; specifically, bovine herpesvirus-1 (bhv-1) (22 of 157, 14%), cervid herpesvirus-1 (17 of 157, 10.8%), and caprine herpesvirus-1 (11 of 159, 6.9%). titers ranged from 4 to 10 ...200617255452
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