Publications

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on the diversity of malaria parasites in african apes and the origin of plasmodium falciparum from bonobos.the origin of plasmodium falciparum, the etiological agent of the most dangerous forms of human malaria, remains controversial. although investigations of homologous parasites in african apes are crucial to resolve this issue, studies have been restricted to a chimpanzee parasite related to p. falciparum, p. reichenowi, for which a single isolate was available until very recently. using pcr amplification, we detected plasmodium parasites in blood samples from 18 of 91 individuals of the genus pa ...201020169187
origin of the human malaria parasite plasmodium falciparum in gorillas.plasmodium falciparum is the most prevalent and lethal of the malaria parasites infecting humans, yet the origin and evolutionary history of this important pathogen remain controversial. here we develop a single-genome amplification strategy to identify and characterize plasmodium spp. dna sequences in faecal samples from wild-living apes. among nearly 3,000 specimens collected from field sites throughout central africa, we found plasmodium infection in chimpanzees (pan troglodytes) and western ...201020864995
a cautionary note on fecal sampling and molecular epidemiology in predatory wild great apes.fecal samples are an important source of information on parasites (viruses, prokaryotes, or eukaryotes) infecting wild great apes. molecular analysis of fecal samples has already been used for deciphering the origins of major human pathogens such as hiv-1 or plasmodium falciparum. however, for apes that hunt (chimpanzees and bonobos), detection of parasite nucleic acids may reflect either true infection of the host of interest or ingestion of an infected prey, for example, another non-human prim ...201526031302
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