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[canine distemper virus--an agent looking for new hosts].canine distemper is caused by the canine distemper virus (cdv), a rna virus belonging to the genus morbillivirus of the family paramyxoviridae. the genus morbillivirus includes measles virus, rinderpest virus and peste-des-petits-ruminants virus. the host spectrum of cdv, which includes numerous families of carnivores, has been changed in the last years and distemper-like diseases have been observed in numerous other species. these include epidemics in large felids, marine mammals and javelinas. ...200312756952
the role of canine distemper virus and persistent organic pollutants in mortality patterns of caspian seals (pusa caspica).persistent organic pollutants are a concern for species occupying high trophic levels since they can cause immunosuppression and impair reproduction. mass mortalities due to canine distemper virus (cdv) occurred in caspian seals (pusa caspica), in spring of 1997, 2000 and 2001, but the potential role of organochlorine exposure in these epizootics remains undetermined. here we integrate caspian seal mortality data spanning 1971-2008, with data on age, body condition, pathology and blubber organoc ...201424987857
a histopathology study of caspian seal (pusa caspica) (phocidae, mammalia) liver infected with trematode, pseudamphistomum truncatum (rudolphi, 1819) (opisthorchidae, trematoda).main objective of this study was to investigate the invasive activity of the liver fluke, pseudamphistomom truncatum against the caspian seal (pusa caspica) and was exemplified at the gross, light microscopy (lm) and electron microscopy (em) levels.201725848395
persistent organic pollutants (pops) in caspian seals of unusual mortality event during 2000 and 2001.persistent organic pollutants including organochlorine pesticides, pcbs, and pcdds/dfs were determined in the blubber of caspian seals, which died during an outbreak of canine distemper virus in 2000 and 2001. ddts were the predominant contaminants that ranged from 3.1 to 560 microg/g lipid. a negative correlation was observed between concentration of contaminants and blubber thickness. during spring, as the blubber layer becomes thin after breeding and moulting, seals may face higher risk due t ...200817900768
the 2000 canine distemper epidemic in caspian seals (phoca caspica): pathology and analysis of contributory factors.more than 10,000 caspian seals (phoca caspica) were reported dead in the caspian sea during spring and summer 2000. we performed necropsies and extensive laboratory analyses on 18 seals, as well as examination of the pattern of strandings and variation in weather in recent years, to identify the cause of mortality and potential contributory factors. the monthly stranding rate in 2000 was up to 2.8 times the historic mean. it was preceded by an unusually mild winter, as observed before in mass mo ...200616672579
organochlorine and organotin compounds in caspian seals (phoca caspica) collected during an unusual mortality event in the caspian sea in 2000.polychlorinated biphenyls (pcbs), organochlorine pesticides and organotin compounds were determined in the blubber and liver of caspian seals (phoca caspica) found stranded on the coast of the caspian sea during an outbreak of canine distemper virus (cdv) in 2000. among organochlorines analyzed, ddts were the most dominant contaminants with concentrations ranging from 6.3 to 470 microg/g on a lipid-weight basis. caspian seals collected in 2000 during the epizootic had higher concentrations of or ...200211911523
elevated concentrations of trace elements in caspian seals (phoca caspica) found stranded during the mass mortality events in 2000.concentrations of v, mn, fe, cr, co, cu, zn, as, se, mo, ag, cd, tl, hg, pb, and organic mercury (org-hg) were determined in liver, kidney, and muscle of healthy caspian seals ( phoca caspica) collected in 1998. these concentrations were compared with those of seals infected with canine distemper virus (cdv) found stranded along the coastal areas in 2000. concentrations of toxic elements (as, ag, cd, tl, hg, pb, and org-hg) in caspian seals stranded in 2000 were comparable or lower than those of ...200211910465
mass die-off of caspian seals caused by canine distemper virus.thousands of caspian seals (phoca caspica) died in the caspian sea from april to august 2000. lesions characteristic of morbillivirus infection were found in tissue specimens from dead seals. canine distemper virus infection was identified by serologic examination, reverse transcriptase- polymerase chain reaction, and sequencing of selected p gene fragments. these results implicate canine distemper virus infection as the primary cause of death.200011076723
canine distemper virus in a caspian seal. 19989885131
[molecular-genetic comparison of morbilliviruses which caused epizooty in baikal (phoca siberica) and caspian (phoca caspica) seals].the nucleotide sequences were determined for a phosphoprotein gene fragment of canine distemper virus (cdv) by using the rt-pcr method with the subsequent sequencing of amplicons from total rna isolated from 2 samples of caspian seals, 15 samples of baikal seals and from samples of dog's and sea-lion's brains. the above materials were phylogenetically analyzed. the heterogeneity of the virus circulating in the baikal-seal population was demonstrated. morbillivirus, that caused epizooty in caspia ...200314664160
caspian seal die-off is caused by canine distemper virus. 200111239773
virology. canine virus blamed in caspian seal deaths.canine distemper virus has been identified as the most likely cause of a die-off of thousands of seals in the caspian sea earlier this year. although the findings by two independent research groups allay fears of a threat to humans, they heighten concerns about the survival of the imperiled species.200011032547
cross-species transmission of canine distemper virus-an update.canine distemper virus (cdv) is a pantropic morbillivirus with a worldwide distribution, which causes fatal disease in dogs. affected animals develop dyspnea, diarrhea, neurological signs and profound immunosuppression. systemic cdv infection, resembling distemper in domestic dogs, can be found also in wild canids (e.g. wolves, foxes), procyonids (e.g. raccoons, kinkajous), ailurids (e.g. red pandas), ursids (e.g. black bears, giant pandas), mustelids (e.g. ferrets, minks), viverrids (e.g. civet ...201528616465
retrospective differentiation of canine distemper virus and phocine distemper virus in phocids.formalin-fixed paraffin-embedded tissues from one caspian seal (phoca caspica), one harp seal (phoca groenlandica), one hooded seal (cystophora cristata), and one harbor seal (phoca vitulina vitulina) were used to compare the utility of immunohistochemistry (ihc) versus that of a novel seminested reverse transcriptase polymerase chain reaction (rt-pcr) to detect and differentiate canine distemper virus (cdv) and phocine distemper virus (pdv). four antibodies made against pdv were able to detect ...200415137488
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