low genetic diversities of rabies virus populations within different hosts in brazil.the low rates of nonsynonymous evolution observed in natural rabies virus (rabv) isolates are suggested to have arisen in association with the structural and functional constraints operating on the virus protein and the infection strategies employed by rabv within infected hosts to avoid strong selection by the immune response. in order to investigate the relationship between the genetic characteristics of rabv populations within hosts and the virus evolution, the present study examined the gene ...201020018256
host and viral traits predict zoonotic spillover from mammals.the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ...201728636590
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