| comparative analysis of protein unfoldedness in human housekeeping and non-housekeeping proteins. | absence of any regular structure is increasingly being observed in structural studies of proteins. these disordered regions or random coils, which have been observed under physiological conditions, are indicators of protein plasticity. the wide variety of interactions possible due to the flexibility of these 'natively disordered' regions confers functional advantage to the protein and the organism in general. this concept is underscored by the increasing proportion of intrinsically unstructured ... | 2004 | 15238363 |