Publications

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[nobel prize for physiology or medicine 2002 is awarded for research into the genetic regulation of organ development and programmed cell death].the human body consists of hundreds of cell types, all originating from one fertilized egg. during the embryonic and foetal periods, the number of each cell type increases dramatically. the cells mature and become specialised to form the various tissues and organs of the body. large numbers of cells are also formed in the adult body. cell death is a normal process, which runs parallel to this generation of new cells. it takes place in both the foetus and adult, thereby maintaining the appropriat ...200212532662
[sydney brenner, robert horvitz and john sulston. winners of the 2002 nobel prize in medicine or physiology. genetic regulation of organ development and programmed cell death]. 200212451938
worm cast in starring role for nobel prize. 200212374942
[nobel prize 2002. organ development and programmed cell death]. 200312557028
a nice development: the first joint meeting of the british and french societies for developmental biology, 13-16th september, 2003, nice, france.held this autumn on the beautiful cote d'azur, the first joint meeting of the bsdb and sfbd provided delegates with the perfect informal setting for discussion spanning a broad cross-section of developmental biology. participants' interests were diverse, ranging from the implementation of genome-wide approaches aimed at identifying all the molecular components of cell proliferation, signalling, patterning, and morphogenesis, to those engaged in capturing mesmerising glimpses of the minute and in ...200415162518
[nobel prize in physiology or medicine 2002]. 200212569703
ppw-1, a paz/piwi protein required for efficient germline rnai, is defective in a natural isolate of c. elegans.one of the remarkable aspects about rna interference (rnai) in caenorhabditis elegans is that the trigger molecules, dsrna, can be administered via the animal's food. we assayed whether this feature is a universal property of the species by testing numerous strains that have been isolated from different parts of the globe. we found that one isolate from hawaii had a defect in rnai that was specific to the germline and was a result of multiple mutations in a paz/piwi domain-containing protein, wh ...200212225671
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