Publications

a serological survey of australian wildlife for antibodies to leptospires of the hebdomadis serogroup.	a serological survey for antibodies to leptospira interrograns serovar hardjo was conducted on 574 serum samples from 10 native and 4 introduced wildlife species in south-eastern australia. the microscopic agglutination (ma) test was used, and titres to hardjo antigen were detected in 33.5% of 352 brushtailed possums (trichosurus vulpecula) sampled in several areas of victoria. prevalence of reactors ranged from 14 to 66% in 4 populations examined intensively. serovar balcanica was isolated from ...	1979	485984
levels of trace elements in the liver and diet of free-living koalas, phascolarctos cinereus (goldfuss).	the mean liver concentrations of copper, manganese, zinc and cobalt were 0.25, 0.20, 2.97 mmol/kg and 2.81 mumol/kg respectively in free-living koalas in victoria, australia. the mean plasma copper concentration was 9.2 mmol/liter which was somewhat below the level in other hindgut fermenters. the mean concentrations of copper, manganese and zinc in their diet (eucalyptus spp.) were 0.08, 4.46 and 0.27 mmol/kg respectively. analysis of the data established a significant correlation between the a ...	1984	6492324
enzyme-linked immunosorbent assays for detecting antibody to rickettsia australis in sera of various animal species.	new endemic areas of spotted fever-like rickettsial disease have been found in south-eastern australia (gippsland, victoria and flinders island, tasmania). the rickettsia responsible is currently unknown although it may be rickettsia australis. to investigate serological evidence of rickettsial exposure in various wild animal species, a competitive elisa was developed which detected antibodies to r. australis. it was based on inhibition of an indirect elisa detecting antibody to r. australis in ...	1990	2292182
spotted fever group rickettsial infection in south-eastern australia: isolation of rickettsiae.	flinders island spotted fever (fisf), a spotted fever group (sfg) rickettsial disease first described in 1991, occurs in south-eastern australia. the isolation of the aetiological agent is described for the first time having been obtained from the blood of two patients. an additional 22 cases are also reported. of these patients four had positive initial serology, and 20 showed seroconversion (using rickettsia australis as antigen). acute phase blood specimens taken from seven patients caused ne ...	1993	8403837
possible involvement of post-dopamine d2 receptor signalling components in the pathophysiology of schizophrenia.	par-4 has been suggested to mediate dopamine neurotransmission. dopamine d2 receptor (drd2) activation induces a signalling complex of akt1, pp2a and beta-arrestin2 which dephosphorylates/inactivates akt1 thereby activating gsk-3beta, transducing dopamine-dependent behaviour. drd2 activation also results in down-regulation of pka activity. among other substrates pka phosphorylates gsk-3beta. prolonged drd2 activation leads to its 'desensitization' which involves grks and beta-arrestins. beta-arr ...	2008	17681085
increasing rates and clinical consequences of nalidixic acid-resistant isolates causing enteric fever in returned travellers: an 18-year experience.	the purpose of this study was to examine the rate and clinical consequences of nalidixic acid-resistant (nar) isolates in travellers with enteric fever presenting to a hospital in a developed country. we retrospectively examined microbiologically confirmed cases of enteric fever in adult returned travellers over an 18-year period presenting to two tertiary referral hospitals in melbourne, australia. there were 59 cases of salmonella typhi infection, 43 cases of s. paratyphi a infection and two c ...	2009	19357879