| antibodies to borrelia burgdorferi in rodents in the eastern and southern united states. | serologic studies were conducted to determine whether white-footed mice (peromyscus leucopus) and cotton mice (peromyscus gossypinus) contained serum antibodies to borrelia burgdorferi, the causative agent of lyme borreliosis. enzyme-linked immunosorbent assays detected antibodies to this spirochete in 35.7 and 27.3% of 56 p. leucopus and 535 p. gossypinus serum samples, respectively, collected in connecticut, north carolina, south carolina, georgia, florida, alabama, and mississippi. antibody t ... | 1992 | 1624561 |
| antibodies to borrelia burgdorferi in deer and raccoons. | an enzyme-linked immunosorbent assay (elisa) was developed to detect serum antibodies to borrelia burgdorferi, the causative agent of lyme borreliosis, in deer (odocoileus virginianus) and raccoons (procyon lotor). blood samples were collected from these mammals in connecticut, maryland, north carolina, georgia and florida. seropositivity for deer was highest in connecticut (56% of 353 sera) and maryland (51% of 35 sera). raccoons in connecticut, maryland, north carolina, and florida also had an ... | 1991 | 1758022 |
| borrelia burgdorferi in ticks (acari: ixodidae) from coastal virginia. | ixodid ticks removed from hosts and from vegetation during march-november 1987 at sites in coastal virginia and north carolina were examined for borrelia burgdorferi. b. burgdorferi was evident in nine (22%) ixodes cookei packard removed from rice rats (oryzomys palustris), a white-footed mouse (peromyscus leucopus), and raccoons (procyon lotor); four (6%) amblyomma americanum (l.) removed from raccoons; and two (3%) dermacentor variabilis (say) removed from a raccoon and a rice rat. b. burgdorf ... | 1991 | 1941936 |
| antibodies to borrelia burgdorferi in dogs in north carolina. | an indirect immunofluorescence assay was used to detect antibodies against borrelia burgdorferi in sera from 600 dogs in 1983 and 402 dogs in 1985. in 1983, the overall prevalence rate of dogs with b burgdorferi titers greater than or equal to 1:64 was 3.6%, whereas in 1985, the prevalence rate was 2.7%. an unexplainable higher seroprevalence was detected in 1 group of dogs tested in 1983. these dogs were from the southern coastal plains of north carolina. in the dogs tested in 1985, this region ... | 1988 | 3288020 |
| immunoblot analysis of immunoglobulin g response to the lyme disease agent (borrelia burgdorferi) in experimentally and naturally exposed dogs. | immunoblots were used to study the immunoglobulin g response to borrelia burgdorferi in experimentally and naturally exposed dogs. adsorption studies confirmed that the antibodies were specific for b. burgdorferi. experimentally exposed dogs were asymptomatic. naturally exposed dogs included both asymptomatic animals and animals showing signs compatible with lyme disease. naturally exposed dogs were from four geographic regions of the country. no differences were detected between immunoblot patt ... | 1988 | 3366860 |
| spirochetes in ticks and antibodies to borrelia burgdorferi in white-tailed deer from connecticut, new york state, and north carolina. | ticks were screened for spirochetes and serum samples from white-tailed deer (odocoileus virginianus) were assayed for antibodies to borrelia burgdorferi during 1983-1984. using fluorescein isothiocyanate-labeled rabbit antibodies produced to b. burgdorferi, the etiologic agent of lyme disease, spirochetes were detected in ixodes dammini (10.5% of 1,193) and dermacentor albipictus (0.6% of 157) adults from connecticut, i. dammini nymphs (49.1% of 108) and adults (64.7% of 99) from armonk, new yo ... | 1986 | 3520030 |
| tick-raccoon associations and the potential for lyme disease spirochete transmission in the coastal plain of north carolina. | raccoons (procyon lotor) were live-trapped and examined for ticks from july 1990 to july 1993 in the coastal plain of north carolina on marine corps base, camp lejeune, north carolina (usa). five species of ixodid ticks were found on 351 (78%) of 449 raccoons. amblyomma americanum was the most abundant tick found on raccoons. dermacentor variabilis, ixodes texanus, and ixodes scapularis were frequently collected, while ixodes cookei were rarely collected from raccoons. tick burdens were not affe ... | 1997 | 9027688 |
| ability of the lyme disease spirochete borrelia burgdorferi to infect rodents and three species of human-biting ticks (blacklegged tick, american dog tick, lone star tick) (acari:ixodidae). | the infectivity of a diverse collection of borrelia burgdorferi strains from north america for mice was determined as a prelude to vector competence experiments with the 3 primary human-biting tick species in the eastern united states (ixodes scapularis say, dermacentor variabilis (say), amblyomma americanum (l.)]. of the 34 b. burgdorferi strains inoculated into mice, 29 were infectious; the exceptions were 5 isolates from texas. vector competence experiments were conducted with 2 strains from ... | 1997 | 9220680 |
| erythema migrans-like rash illness at a camp in north carolina: a new tick-borne disease? | borrelia burgdorferi, the causative agent of lyme disease, has never been isolated from a patient thought to have acquired lyme disease in any southeastern state. | 1997 | 9531233 |
| reported distribution of ixodes scapularis and ixodes pacificus (acari: ixodidae) in the united states. | lyme disease, caused by infection with borrelia burgdorferi, is the most frequently reported arthropod-borne disease in the united states. to develop a national map of the distribution of the vectors of b. burgdorferi to humans (ixodes scapularis say and ixodes pacificus cooley & kohls ticks), we sent questionnaires to acarologists, health officials, and lyme disease researchers; surveyed the 1966-1996 medline data base; and reviewed 1907-1995 national tick collection data. tick collection metho ... | 1998 | 9775584 |
| ticks and antibodies to borrelia burgdorferi from mammals at cape hatteras, nc and assateague island, md and va. | results of a survey for ixodid ticks and/or serum antibodies to borrelia burgdorferi from 14 species of small to large mammals from eastern coastal areas of the united states are presented. most samples were obtained from july 1987 through june 1989 (excluding december-march) at 3 locales: assateague is. national seashore, worcester co., md., and accomack co., va. (approximately 38 degrees 05' n 75 degrees 10' w), and cape hatteras national seashore, dare co., nc (approximately 35 degrees 30' n ... | 1999 | 10534951 |
| characterization of lyme disease spirochetes isolated from ticks and vertebrates in north carolina. | borrelia burgdorferi isolates obtained from numerous locations and from different hosts in north carolina, were compared to previously characterized strains of the lyme disease spirochete and other borrelia spp. the spirochete isolates were confirmed to be b. burgdorferi sensu stricto based on immunofluorescence (ifa) using a monoclonal antibody to outer surface protein a (osp a [h5332]) and polymerase chain reaction (pcr) using a species-specific nested primer for a conserved region of the gene ... | 2000 | 10682743 |
| lyme disease. pitfalls in diagnosis. | | 2000 | 11103605 |
| bartonella henselae igg antibodies are prevalent in dogs from southeastern usa. | in contrast to the large body of literature regarding bartonella henselae in humans and cats, there is little information about b. henselae as an infectious agent in dogs. due to the paucity of information regarding the b. henselae serology in dogs, we performed a cross-sectional serosurvey using b. henselae antigen in order to compare the seroprevalence between sick and healthy dogs from the south-eastern usa. ninety-nine sera were collected from clinically healthy dogs. three hundred and one s ... | 2004 | 15369661 |
| the dog as a sentinel for human infection: prevalence of borrelia burgdorferi c6 antibodies in dogs from southeastern and mid-atlantic states. | lyme disease is the most frequently reported human vector-associated disease in the united states. infection occurs after the bite of an ixodid tick that is infected with borrelia burgdorferi. dogs have often been reported to serve as effective sentinel animals to assess the risk of human b. burgdorferi infection. based on published data of human lyme disease case numbers and our clinical impressions, we hypothesized that canine exposure to b. burgdorferi would be lower in north carolina when co ... | 2004 | 15631067 |
| the dog as a sentinel for human infection: prevalence of borrelia burgdorferi c6 antibodies in dogs from southeastern and mid-atlantic states. | lyme disease is the most frequently reported human vector-associated disease in the united states. infection occurs after the bite of an ixodid tick that is infected with borrelia burgdorferi. dogs have often been reported to serve as effective sentinel animals to assess the risk of human b. burgdorferi infection. based on published data of human lyme disease case numbers and our clinical impressions, we hypothesized that canine exposure to b. burgdorferi would be lower in north carolina when co ... | 2005 | 16011425 |
| serologic evaluation of patients from missouri with erythema migrans-like skin lesions with the c6 lyme test. | southern tick-associated rash illness (stari), also known as masters disease, affects people predominantly in the southeast and south central united states. these patients exhibit skin lesions that resemble erythema migrans (em), the characteristic skin lesion in early lyme disease. the etiology of stari remains unknown, and no serologic test is available to aid in its diagnosis. the c6 lyme enzyme-linked immunosorbent assay was used to evaluate coded serum specimens from patients with stari at ... | 2006 | 17028220 |
| detection of rickettsia amblyommii in association with a tick bite rash. | in the summer of 2006, an amblyomma americanum tick was removed from a woman in central north carolina, who subsequently developed a rash at the site of tick attachment. when examined by polymerase chain reaction (pcr) for borrelia, anaplasma, ehrlichia, babesia, rickettsia, and bartonella dna, only the rickettsia primers generated an amplicon, which was identified as "r. amblyommii" by sequencing. to our knowledge, this is the first case in which r. amblyommii was temporally associated with a r ... | 2007 | 18052716 |
| bacterial pathogens in ixodid ticks from a piedmont county in north carolina: prevalence of rickettsial organisms. | in north carolina, reported human cases of tick-borne illness, specifically rocky mountain spotted fever, have escalated over the past decade. to determine the relative abundance of vectors and to estimate the risk of acquiring a tick-borne illness in peri-residential landscapes, ticks were collected in chatham county, a typical piedmont county and, samples of the ticks were tested for infection with selected bacterial pathogens using real-time quantitative polymerase chain reaction assays. tick ... | 2010 | 20455778 |
| recent discovery of widespread ixodes affinis (acari: ixodidae) distribution in north carolina with implications for lyme disease studies. | ixodes affinis, which is similar morphologically to ixodes scapularis, is widely distributed in north carolina. collections have documented this species in 32 of 41 coastal plain counties, but no piedmont or mountain counties. this coastal plain distribution is similar to its distribution in georgia and south carolina, where it is considered an enzootic vector of borrelia burgdorferi sensu stricto. an updated list of hosts for i. affinis in the u.s.a. is included, increasing the number to 15 mam ... | 2010 | 20618664 |
| borrelia species in ixodes affinis and ixodes scapularis ticks collected from the coastal plain of north carolina. | ixodes affinis and i. scapularis are tick species that are widely distributed in the coastal plain region of north carolina. both tick species are considered enzootic vectors for spirochetal bacteria of the genus borrelia and specifically for b. burgdorferi s.s., the pathogen most often attributed as the cause of lyme disease in the usa. laboratory testing of individual i. affinis and i. scapularis ticks for the presence of borrelia dna was accomplished by pcr, targeting 2 regions of the 16s-23s ... | 2010 | 21771524 |