| hepatitis b virus dna in serum and liver is commonly found in chinese patients with chronic liver disease despite the presence of antibodies to hbsag. | sera from 410 patients from the wuhan area in the central part of china with the diagnosis of chronic liver disease were analyzed for markers of hepatitis b, c and d virus infections. all sera, plus liver biopsy specimens from 188 of the patients, were also tested for hepatitis b virus dna by polymerase chain reaction. sixty-eight percent were hbsag positive in serum, whereas 29% showed markers of past hepatitis b virus infection. hepatitis b virus dna was detected in all hbeag-positive sera but ... | 1993 | 7682978 |
| molecular epidemiology of human immunodeficiency virus type 1 and hepatitis c virus in former blood donors in central china. | the prevalence of hepatitis c virus (hcv) among human immunodeficiency virus (hiv-1)-positive former blood donors (fbds) in hubei province, central china, and the subtypes of these two viruses are identified. hiv-1-positive specimens were collected from fbds, transfusion recipients, and their sexual partners in hubei province, central china. the prevalence of hcv in hiv-1-positive fbds was 78.6%. the dominant circulating hiv-1 subtype of fbds was subtype b' (thai-b); one belonged to u.s.-europea ... | 2008 | 18275341 |
| epidemiology of hepatitis c virus infection among injection drug users in china: systematic review and meta-analysis. | injection drug use (idu) is the predominant mode of hepatitis c virus (hcv) transmission in china. this paper aims to provide a comprehensive and reliable tabulation of available data on the epidemiological characteristics and risk factors for hcv infection in injection drug users (idus) in china to help inform prevention programmes and guide future research. | 2008 | 18486955 |
| antibodies to hepatitis c virus and hepatitis c virus rna in chinese blood donors determined by elisa, recombinant immunoblot assay and polymerase chain reaction. | antibodies to hepatitis c virus (anti-hcv) were determined in chinese blood donors from the city of wuhan by elisa screening tests and confirmatory recombinant immunoblot assay (riba). 281 and 222 sera were sampled under similar conditions in 1989 and 1990, respectively. the first collection of sera was sent to sweden in lyophilized form, the second directly as fresh, unfrozen sera. a high proportion (22%) of the lyophilized sera were positive in the screening assay but only 6 (2.10%) were posit ... | 1993 | 7686839 |
| hepatitis c virus infection in different groups of children in wuhan area. | to investigate the incidence of child's hcv infection in our area, 637 children with different background, including 65 posttransfusion cases, 419 hepatitis patients (250 cases of acute hepatitis a, 156 cases of chronic hepatitis b and 13 cases of non-a, non-b hepatitis), 50 infantile hepatitis syndrome (ihs) infants and 103 healthy day-cared children were tested for serum anti-hcv antibody (eia) and hcv rna (nested pcr). it was found that posttransfusion children had significantly higher anti-h ... | 1993 | 7512151 |
| hepatitis c virus antibodies and hepatitis c virus rna in chinese blood donors determined by elisa, recombinant immunoblot assay and polymerase chain reaction. | antibodies to hepatitis c virus (anti-hcv) were determined in chinese blood donors from the city of wuhan by a second generation elisa screening test and a confirmatory recombinant immunoblot assay (riba ii). two materials of 281 and 222 sera were sampled under similar conditions in 1989 and 1990, respectively. the first collection of sera was sent to sweden in lyophilized form, the second directly as fresh unfrozen sera. a high proportion (7.1%) of the lyophilized sera reacted positively in the ... | 1992 | 1382461 |
| [analysis of hiv/syphilis/hcv infection among drug users in 15 cities, china]. | to study the hiv infection rate and relevant behavioural characteristics among drug users (dus) in the 15 cities of china-gates hiv/aids program. | 2010 | 21215121 |
| [a study of mix-infections with different genotypes of hepatitis c virus in patients from a methadone maintenance clinic in wuhan]. | | 2009 | 19565893 |
| systematic review of hiv and hcv infection among drug users in china. | to determine the hiv and hepatitis c virus (hcv) geographical distribution among drug users in china, a systematic literature review of 40 peer-reviewed publications (comprising 15,565 drug users) was conducted. of the total drug users, 10,724 were found to be injection drug users (idus) and 4841 were non-injection drug users (non-idus). various studies identified that among idus and non-idus, the overall hiv prevalence rates were 12.55% and 1.05%, and the hcv prevalence rates were 66.97% and 18 ... | 2009 | 19451325 |
| [study on the distribution of hepatitis c virus genotypes in patients visiting one methadone maintenance clinic in wuhan]. | to study the prevalence of hepatitis c virus (hcv) infection and characteristics on molecular biology related to hcv among patients who were enrolled in a methadone maintenance clinic in wuhan. | 2007 | 18476583 |
| genetic variation of hepatitis c virus in a cohort of injection heroin users in wuhan, china. | since the majority of heroin abusers use injection as the primary route of admission, heroin abuse contributes significantly to the transmission of hepatitis c virus (hcv). we determined hcv infection and its genotype distribution among injection heroin users in wuhan, the largest city in the central china. eight hundred seventy-eight (84%) out of 1046 serum specimens from the injection drug users were positive for hcv antibody. out of randomly selected 122 specimens positive for hcv antibody, s ... | 2008 | 18353479 |