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seroepidemiologic studies of acute hemorrhagic conjunctivitis virus (enterovirus type 70) in west africa. i. studies with human sera from ghana collected eight years after the first outbreak.in 1969 and early 1970, during the pre-epidemic period of acute hemorrhagic conjunctivitis (ahc) in the upper north regions of ghana, 191 human sera were collected. in 1977, eight years after the first epidemic of ahc in ghana, 1008 human sera were also collected in various regions of ghana. these sera were examined for virus neutralizing (vn) antibody against the j670/71 strain of enterovirus type 70 (ev70). in the pre-epidemic 1969-1970 sera, a low prevalence rate (6%) of vn antibody, with a t ...19817304562
a study of the evolution of coxsackievirus a24 variant in ghana by viral rna fingerprinting analysis.an epidemic of acute haemorrhagic conjunctivitis (ahc) caused by coxsackievirus a24 variant (ca24v) was reported in accra, ghana in may 1987. we studied 7 of the viral strains collected from may to november, 1987, by rna genome fingerprinting. pairwise comparisons of the oligonucleotide maps showed that genetic similarity among them ranged from between 60.0 to 84.7%. using base sequence variations deduced from genetic similarity among the isolates, isolation time of the strains and the rate of n ...19912052752
epidemic acute haemorrhagic conjunctivitis due to coxsackie virus a24 variant in ghana.an outbreak of acute haemorrhagic conjunctivitis (ahc) occurred in accra, ghana, reaching a peak in july 1987. individuals ranging from infants to adults over 50 years were infected, with those between 20 and 30 years being the most affected group. there was a female preponderance. clinical features included conjunctivitis, subconjunctival haemorrhage and ocular pain. some patients reported of blurred vision due to mild keratitis. isolation of virus from clinical specimens of ahc patients was su ...19901964635
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