| a study of macrophage-mediated initiation of fibrosis by asbestos and silica using a diffusion chamber technique. | several cellular interactions have been identified as potentially important in fibrogenesis induced by mineral dusts. evaluation of their relative importance in vivo remains a problem. sealed diffusion chambers limited by nuclepore membranes and implanted into mouse peritoneal cavities provide a means of assessing different stages of fibrogenesis by separating initiating mechanisms (dust-macrophage-lymphocyte combinations inside the chamber) from the target tissue. fibrous reactions surrounding ... | 1982 | 6817777 |