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[congenital malaria: clinical, parasitological and histological considerations. apropos of 200 observations collected at the lomé university teaching hospital and kpalimé hospital].an evaluation was conducted of the usefulness of clinical, parasitological and histological parameters for the diagnosis of neonatal pathology due to congenital malaria. haematozoa detected were invariably plasmodium falciparum. their presence in the placenta was considered essential to confirm congenital infection, but needed always to be accompanied by a positive diagnose of the same species in the mother, villous vessels, umbilical cord and peripheral blood of the newborn child. none of these ...19911819393
[infectious profile of the newborn in a pediatric unit in a regional hospital center in togo].in one year 106 suspect cases of neo-natal infection were admitted to the pediatric ward of chr in kara. the principal elements of diagnosis (slow labor, premature membrane rupture, troubled or fetid amniotic fluid, other obstetrical maneuvers or neo-natal reanimation) were related to insufficient follow-up during pregnancy. given the lack of means for microbiologic investigation we were unable to identify any etiologic agent apart for plasmodium. however, therapeutic response indicated infectio ...19911819424
[effects od iron supplementation on malaria infection].an iron supplementation trial had been performed in a southern village of togo during the rainy season when occurs malaria transmission. 241 infants from 6 to 36 months old were matched in two randomized groups. the first one (g1) received oral iron supplementation every day during three months. the second group (g2) received placebo. tablet administration was double blind made. a third group (g3) had been created from two others with anaemic infants and received daily iron supplementation. thre ...19912065403
antimalarial effects of eight african medicinal plants.crude hot water extracts from eight medicinal plants collected in togo, west africa, were examined for antimalarial properties against plasmodium falciparum using an in vitro test. the activity differed with the plant species with extracts of cassia siamea, jatropha gossypiifolia and pavetta crassipes capable of 100% inhibition.19892654489
[chloroquine-resistant plasmodium falciparum in togo. a case]. 19872962093
[emergence of chloroquine-resistant malaria in west africa: the case of sokode (togo)].within the framework of its surveillance of plasmodium falciparum chloroquine sensitivity in eight west african countries (benin, burkina faso, côte d'lvoire, mali, mauritany, niger, senegal, and togo) the reference centre for chemoresistant malaria (crcp) at the organization for coordination and cooperation to control major endemic diseases (o.c.c.g.e.) conducted an in vivo survey in february, 1987, in sokodé (togo). two groups of 67 children, aged 2 to 9, received, for the first group a single ...19883051292
failure of chloroquine treatment to prevent malaria in americans in west africa. 19873312654
single-dose chloroquine therapy for plasmodium falciparum in children in togo, west africa.chloroquine, in a single dose of 10 mg of base/kg, was given orally to togolese children less than 5 years of age as primary therapy for plasmodium falciparum malaria. a simplified world health organization in vivo method was used, as was a sequential analysis procedure for determining if the drug trial was a success or failure. a total of 178 children in 3 regions were treated; 174 (98%) responded successfully, which required a greater than or equal to 75% reduction in parasites by day 2 and el ...19873555135
[congenital malaria. a case observed in twins born to an asymptomatic mother].even in endemic zones, congenital malaria, first described in 1876, is rarely encountered. the incidence has greatly increased however over the last 10 years suggesting several diagnostic problems. we observed a case of infected twins born to an asymptomatic mother which would throw some light on the pathophysiology involved in congenital transmission. a 2-month old infant was hospitalized for surgical cure of an umbilical hernia. haemolytic anaemia (6.3 g/dl) and fever (39 degrees c) were obser ...19948078837
[plasmodium falciparum malaria: type r1 resistance to quinine in west africa]. 19989767965
[relative failure of mefloquine chemoprophylaxis on the occasion of a trip to togo. 3 cases within the same family].in france, 3,500 to 4,000 cases of imported malaria are observed annually. outcome is fatal in 30 to 50 patients, usually because of inappropriately applied preventive measures. we report three cases of imported malaria despite well-conducted chemoprophylaxis.19989819587
chloroquine efficacy in the treatment of uncomplicated malaria at three sentinel sites in northern togo.in togo, chloroquine (cq) remains the first-line drug for the treatment of uncomplicated, plasmodium falciparum malaria. in the absence of recent data on the level of parasite resistance to antimalarial drugs, togo's national malaria control programme (nmcp) decided to assess the current efficacy of cq in the treatment of uncomplicated, p. falciparum malaria at three sentinel sites in the north of the country. between the september and november of 2001, the world health organization's standard 1 ...200314754489
in vitro antiplasmodial activity of crude extracts from togolese medicinal plants.to investigate the antimalarial effect of a few plants in togo folk medicine.201121771436
genetic diversity and genotype multiplicity of plasmodium falciparum infections in symptomatic individuals in the maritime region of togo.objective  to assess the genotype prevalence and the multiplicity of plasmodium falciparum infections in the maritime region of togo. methods  we enrolled 309 symptomatic individuals aged from 6 months to 15 years from bè/lomé and tsévié, two malaria endemic zones. the number and the proportions of merozoite surface proteins 1, 2 and 3 genotypes in patients were determined using capillary electrophoresis genotyping. we further investigated the possible association between transaminases and homoc ...201122074288
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