| molecular surveillance of drug-resistant plasmodium falciparum in two distinct geographical areas of nigeria. | drug resistance against p. falciparum has been recognized as the crucial obstacle to curbing mortality and morbidity from malaria. we therefore determined the baseline distribution of pfcrt and pfmdr1 genes associated with resistance to chloroquine and pfdhfr gene associated with resistance to pyrimethamine in p. falciparum isolates collected from two geographically distinct areas of nigeria. we use rt-pcr assays and sequencing to determine the prevalence of these mutations. the combined prevale ... | 2010 | 21120702 |