amodiaquine treatment of uncomplicated malaria in children, in an area of chloroquine-resistant plasmodium falciparum in north-central nigeria. | the efficacy of amodiaquine against plasmodium falciparum malaria was assessed in an area of confirmed chloroquine resistance in the cool, north-central plateau of nigeria, using a 14-day protocol. the patients were all children aged <5 years of age. the drug proved highly efficacious, giving a cure 'rate' of 100% on day 14 and mean fever- and parasite-clearance times of 1.11 and 3.11 days, respectively. it was also well tolerated. following treatment, packed-cell volumes (pcv) generally increas ... | 2003 | 14613625 |