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[screening of infectious microorganisms in blood banks in douala (1995-2004)].the infection of people with haemophilia by human immunodeficiency virus (hiv) through blood transfusions demonstrated the potential risks of infectious disease transmission by transfusions. the microorganisms that can be transmitted through transfusion include: hepatitis viruses b, c, d, and g, hiv, cytomegalovirus, human t lymphotrophic virus (htlv i and ii), treponema pallidum, brucella spp, toxoplasma gondii, plasmodium spp and trypanosoma cruzi. we estimated the prevalence of transfusion-tr ...200919801344
efficacy of amodiaquine, sulphadoxine-pyrimethamine and their combination for the treatment of uncomplicated plasmodium falciparum malaria in children in cameroon at the time of policy change to artemisinin-based combination therapy.the efficacy of amodiaquine (aq), sulphadoxine-pyrimethamine (sp) and the combination of sp+aq in the treatment of cameroonian children with clinical malaria was investigated. the prevalence of molecular markers for resistance to these drugs was studied to set the baseline for surveillance of their evolution with time.201020105282
antioxidant status of bilirubin and uric acid in patients diagnosed with plasmodium falciparum malaria in douala.oxidative stress and changes in antioxidant status have been implicated in the pathogenesis of malaria. to assess the antioxidant level ofbilirubin and uric acid associated with falciparum malaria infection, 60 untreated patients (30 men and 30 women) in douala, cameroon were screened for the study. sixty five healthy individuals (29 men and 36 women) were used as controls. total and conjugated bilirubin were calculated using jendrassik-grof method while uric acid was determined using barham-tri ...200818819658
[malaria vector control in cameroon: past, present, future. reflections].during the fifties, large scale malaria vector control projects based upon house spraying were implemented in southern and northern parts of cameroon in line of malaria eradication concept. in the south, the pilot zone of yaounde gathered about 150,000 inhabitants, in the forest area. first operations started in 1953 but the programme became actually operational in 1956. it was divided in two parts: the western part was treated with ddt, while the eastern one was treated with dieldrin. at the sa ...200116579079
molecular epidemiology of malaria in cameroon. xi. geographic distribution of plasmodium falciparum isolates with dihydrofolate reductase gene mutations in southern and central cameroon.the dna sequence of the dihydrofolate reductase (dhfr) gene, a molecular marker for pyrimethamine resistance, was determined for 178 field isolates of plasmodium falciparum collected along the east-west axis in southern cameroon. the proportion of isolates having the wild-type dhfr allele varied from 48.1% in the east (city of bertoua) to 11.3-15.7% in central provinces (yaounde and eseka) and 0% in the littoral region (port city of douala). isolates with a single asn-108 mutation or double muta ...200212452492
definition of populations at risk for plasmodium falciparum infection in three endemic areas of cameroon.blood samples were collected from 285 individuals attending hospitals in 1 of 3 different regions of cameroon. of these, 89 had plasmodium falciparum parasitemia. prevalence in the douala region was drastically reduced above the age of 19. in the njinikom and bamenda regions, on the other hand, an appreciable decline in prevalence was not observed until over the age of 49. enzyme-linked immunosorbent assay (elisa) values indicate that in douala, high antibody titers to p. falciparum were present ...19947799161
[2 cases of multiresistant plasmodium falciparum malaria contracted in douala with atypical clinical presentation].we present two cases of plasmodium falciparum malaria contracted in douala despite adequate prophylaxis by fansidar for one and by chloroquine for the other. failure of curative treatment by fansidar for the first case (in vitro chloroquine-resistant strain) and by amodiaquine plus erythromycin for the second. after these therapeutic failures, both patients presented without fever, but with splenomegaly and anaemia. the successful therapeutic was mefloquine.19873319253
[evaluation of practice and costs of vector control on a family level in central africa. ii. douala city (cameroon), july 1988].a knowledge, attitude, practice survey was carried out in july 1988 in douala city, by cluster sampling and household visits. 98% of these households declared being disturbed by mosquitoes (bites, diseases, noise); 91% of families are using a vector control method; the main methods are: bed-nets (48%), insecticide sprays (39.5%) and mosquito coils (36.7%). the average cumulated expense by households for vector control (116.6 ecu/year) and care for diseases attributed to mosquitoes (147.4 ecu/yea ...19902222006
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