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mutations in the pfmdr1, dhfr and dhps genes of plasmodium falciparum are associated with in-vivo drug resistance in west papua, indonesia.this study (conducted in 1996-99) examines the association of mutations in pfmdr1, dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes of plasmodium falciparum with in-vivo drug resistance in west papua, indonesia. initially, 85 patients infected with p. falciparum were treated with chloroquine, of whom 21 were cleared of parasites, 49 had parasitaemias classified as ri, rii or riii resistance and 1 patient had recrudescent parasitaemia. fansidar (pyrimethamine-sulfadoxine) ...200111280065
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