| effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: an open-label randomised trial. | artemisinin-combination therapy (act) is recommended as first-line treatment of falciparum malaria throughout the world, and fixed-dose combinations are preferred by who; whether a single gametocytocidal dose of primaquine should be added is unknown. we aimed to compare effectiveness of four fixed-dose acts and a loose tablet combination of artesunate and mefloquine, and assess the addition of a single gametocytocidal dose of primaquine. | 2010 | 20832366 |
| comparison of chloroquine, sulfadoxine/pyrimethamine, mefloquine and mefloquine-artesunate for the treatment of falciparum malaria in kachin state, north myanmar. | multi-drug resistant falciparum malaria is widespread in asia. in thailand, cambodia and vietnam the national protocols have changed largely to artesunate combined treatment regimens but elsewhere in east and south asia chloroquine (cq) and sulfadoxine-pyrimethamine (sp) are still widely recommended by national malaria control programmes. in kachin state, northern myanmar, an area of low seasonal malaria transmission, the efficacy of cq (25 mg base/kg) and sp (1.25/25 mg/kg), the nationally reco ... | 2004 | 15548314 |