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status of plasmodium falciparum resistance to chloroquine in gujarat, rajasthan and maharashtra states of india.an extended study from 1978-88 revealed that in the western states of india i.e., rajasthan, gujarat and maharashtra; p. falciparum resistance to chloroquine has a scattered pattern in its distribution. however in gujarat, r-iii level of resistance is established in southern districts showing four fold increase from 1.79% in 1985 to 8.2% in 1988. in this area use of some alternate drug is indicated.19902209926
relapse pattern of plasmodium vivax in kheda district, gujarat.a study on relapse pattern of p. vivax in kheda district of gujarat revealed that the relapse rate in p. vivax within 8 months of primary attack was around 40% in untreated cases. it was 2.6% within one year in patients treated with 5-day course of primaquine. relapses occurred more frequently from april to october and 82% relapses occurred within one year of the primary attack. relapses occurred up to 4 years after primary attack but they were less frequent in 3rd and 4th year.19902209933
micro in vitro assessment of plasmodium falciparum sensitivity to chloroquine and mefloquine in gujarat.micro in vitro tests conducted in 1987 in surat district of gujarat on sensitivity status of p. falciparum to chloroquine and mefloquine revealed that the parasite has developed resistance to chloroquine upto 32 pmol. the ed 99 in hazira, gothan and umra areas of the district was found to be 17.3, 18.5 and 8.7 pmol/well for chloroquine and for mefloquine it was 14.5, 4.8 and 6.8 pmol/well respectively. monitoring of p. falciparum resistance is indicated under national malaria eradication program ...19902200725
importance of clinical diagnosis of malaria in national malaria control programme.the study conducted at kheda district, gujarat, revealed that judgement of patient on the basis of symptoms and diagnosis of the doctor were correct in 50 and 27% of the suspected malaria cases respectively. in malaria control programme, emphasis on health education and passive case detection is indicated.19911822457
results of chloroquine sensitivity tests in p. falciparum in some districts of gujarat and maharashtra states. 1979398333
studies on outbreak of malaria in muliad village of kheda district, gujarat.irregular and inadequate surveillance of fever cases, misdiagnosis of positive cases and the near nonexistence of an appropriate monitoring mechanism culminated in an outbreak of malaria in a village of kheda district, gujarat. plasmodium falciparum (pf) resistance to chloroquine must have aided in the increase of pf cases. ddt still appears to be effective against the vector, a. culicifacies in the area. amodiaquine was successful in clearing asexual parasites in 83% cases which were resistant ...19902292319
epidemiological implications of population migration: part i. imported malaria in kheda district, gujarat. 19883077367
epidemiological implications of population migration: part ii. evidence of chloroquine resistant plasmodium falciparum malaria in kheda district, gujarat. 19883077368
genetic markers and malaria. observations in gujarat, india.189 healthy controls and 175 patients suffering from malaria vivax have been investigated with regard to associations between this disease and 22 genetic polymorphisms of the blood (abo, mn, ss, rh, kell, p, lutheran, kidd, duffy, diego, xg; abh-secretor; hp, gc, gm, km; ap, ak, pgm1, 6-pgd, esd; hb variants) significant associations could be demonstrated only for p and hp systems, though in accordance with other investigations it cannot be excluded that the abo system plays also a role in this ...19863512422
epidemiological and entomological features of an outbreak of fever in meghraj block, sabarkantha district, gujarat state (india) in 1980. 19846392409
plasmodium falciparum sensitivity in "in-vivo" and its distribution in geo-ecological zones of gujarat.plasmodium falciparum sensitivity test in "in-vivo" carried out in 450 patients revealed, parasite clearance in 66.45 percent cases with 25 mgm/kg body wt of chloroquine. mean parasite clearance time (mpct) of sensitive and r i, resistant cases reached near parallelism with an early recrudescence in ri cases indicating stabilisation of genetic change in the parasite strain. the analysis of data revealed that proportionately higher resistance was recorded in coastal area having deciduous (wet) fo ...19947989673
epidemiological observations on malaria in villages of buhari phc, surat, gujarat.investigations were carried out in the villages of buhari phc, surat district, gujarat to determine factors responsible for high prevalence of p. falciparum. the area is well-known for sugarcane cultivation, industrialization and frequent movement of labourers. the slide positivity rate (44.24%) and p. falciparum infections (95.37%) were significantly high. the children of 5-9 yrs of age group suffered maximum from malaria. the infection in children was found associated with splenomegaly also. h ...19958867060
a study of sensitivity of p. falciparum to chloroquine in a rural area of bharuch district, gujarat. sewa-rural research team. society for education, welfare and action.a study was undertaken to determine the level of chloroquine sensitivity in p. falciparum strains prevalent in a rural, tribal-belt of bharuch district, gujarat during 1992-93. of the 32 cases for which the 7-day follow-up was completed, only in one rii level of resistance was noted, with the mean parasite clearance time in the remaining cases being 1.87 days. thus, chloroquine continues to be effective in treatment on falciparum malaria in this area.19969014395
studies on plasmodium vivax relapse pattern in kheda district, gujarat.relapse pattern in p. vivax malaria was studied in five villages of nadiad taluka, kheda district, gujarat. p. vivax cases treated with 600 mg chloroquine and in combination with 50 mg pyrimethamine (adult dose) yielded 28.31 and 27.73% relapse rate respectively. while relapse rate of 5.78% was observed with five day course of 75 mg primaquine (15 mg/day) administered as radical treatment. relapse rate in 5-10 yr of age group was comparatively more than other age groups. there was no noticeable ...19969125831
role of geographic information system in malaria control.in this paper we provide an account of our experience in the application of remote sensing (rs) and geographic information system (gis) in understanding malaria transmission dynamics at the local level. two studies have been briefly reviewed. one is the application of rs on the mosquito production in the sanjay lake and surrounding areas in delhi. studies are demonstrated that remote sensing data were useful in assessing relative mosquito abundance from large water bodies. the second study was c ...19979291687
some aspects of changing behaviour of malaria vectors in tribal areas of india.the field entomological studies and surveys carried out in 72 tribal districts out of 100 in seven penninsular states namely, andhra pradesh, bihar, gujarat, madhya pradesh, maharashtra, orissa and rajasthan indicated that in most of the areas the vector mosquitoes encountered during the present study were almost the same as recorded by the earlier workers except that anopheles fluviatilis james, 1902 was recorded in the areas of district raipur, durg, bilaspur, raigarh, shahdol, rajnandgaon, ba ...199810810568
maternal manifestations of malaria in pregnancy: a review.malaria is a major cause of maternal and fetal morbidity and mortality, and this risk is highest in the areas of unstable malaria transmission. in 1990 and 1991 the department of obstetrics and gynecology of sir sayajirao general hospital in central gujarat, india, has cared for a total of 445 urban as well as rural patients with malaria in pregnancy: 232 were labor ward admissions and 213 were antenatal ward admissions. plasmodium falciparum infection affected 97.27% of patients, both primigrav ...199312345925
malaria diagnosis in private laboratories of surat city: a laboratory based study. 200415672561
plasmodium ovale--a case report from gujarat. 200617175709
relationship between malaria and sociocultural aspects in villages along the river mahi in central gujarat.the sociocultural practices of the people differ between communities and play an important role in malaria control operations. the present study was carried out with the aim to understand the association of malaria with sociocultural determinants in malaria prone riverine villages of kheda district in central gujarat. blood smears of persons with fever or having history of fever were collected and examined under microscope for malarial parasite. a structured questionnaire was used to record age, ...200718232174
therapeutic responses of plasmodium vivax and p. falciparum to chloroquine, in an area of western india where p. vivax predominates.in 2003-2005, following an increase in the local incidence of human malaria, the therapeutic efficacy of chloroquine (cq) in the treatment of plasmodium vivax and p. falciparum malaria was evaluated in the anand district of gujarat state, in western india. after oral administration of cq, clinical and parasitological responses were measured over a follow-up period of 28 days, following the standard protocol of the world health organization. most of the recurrent infections were checked, by genot ...200818782486
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