| response of plasmodium falciparum in sudan to oral chloroquine. | the chloroquine sensitivity of plasmodium falciparum was studied in two areas of sudan. in the gezira, 99.2% of the patients tested responded completely to the drug. two patients (0.4%) and one patient (0.2%) showed, respectively, ri and rii responses. however, in those showing ri response reinfection could not be excluded. in an area of southern sudan patients could only be followed-up for 7 days; nevertheless, this was sufficient to exclude the presence of rii and riii responses there. this st ... | 1978 | 362953 |
| assessment of chloroquine resistance of plasmodium falciparum in children of wad medani (central sudan). | the study reports on chloroquine resistance of plasmodium falciparum among sudanese children (6 month to 16 years) living at wad medani, central sudan. all ri-iii levels of resistant response were confirmed, while in vitro sensitivity test indicated that 25 per cent of p. falciparum isolates examined had exhibited maturation of schizonts at cq level greater than or equal to 1.6 pmol/microliters blood. cq was sufficiently retained for 7 days after drug administration whereas an average peak level ... | 1992 | 1527810 |
| an abc-elisa for malaria serology in the field. | an avidin biotin peroxidase complex enzyme-linked immunosorbent assay (abc-elisa) was examined for the diagnosis of malaria in a controlled area in sudan gezira. the titers of the abc-elisa coincided with those of the ifat. the method was more sensitive than the ordinary elisa as the final enzyme reaction was amplified through the use of the abc system. this allowed the resulting color spots on the dried plate wells to be read clearly with the naked eye. this test can be carried out without usin ... | 1990 | 2405725 |
| response of plasmodium falciparum to antimalarial drugs in vitro at wad medani, sudan. | | 1988 | 3052537 |
| malaria parasitemia during delivery. | the aim of this study is to investigate the impact of plasmodium falciparum infection in parturient women in central sudan where malaria transmission is mesoendemic. the purpose of this paper is to find out the prevalence of malaria parasitemia and the risk of anemia among parturient women and to suggest appropriate strategies to lower their prevalence rates. | 2002 | 12070548 |
| malaria case management at the community level in gezira, sudan. | this study was done to investigate malaria case management at the community level in gezira, sudan, which is an area of unstable malaria predominantly due to plasmodium falciparum. questionnaire surveys were conducted at four consecutive weekly intervals in october 1995. a sample of 400 households (3062 persons) including 200 rural and 200 urban households was studied. use of antimalarials was assessed in terms of diagnosis, types of antimalarial used, self-medication and compliance. during the ... | 2001 | 14513938 |
| in vitro study assessing the response of plasmodium falciparum malaria to chloroquine, sulfadoxine/pyrimethamine, quinine and mefloquine in wad medani district, sudan. | to assess the in vitro response of plasmodium falciparum malaria to chloroquine (cq), sulfadoxine/pyrimethamine (sdx/pyr), quinine (qu) and mefloquine (mq) and monitoring their resistance. | 2006 | 16758040 |
| cortisol, prolactin, cytokines and the susceptibility of pregnant sudanese women to plasmodium falciparum malaria. | understanding the hormonal and cytokine interactions that underlie susceptibility to the disease should be helpful in elucidating the pathogenesis of malaria during pregnancy. the current study was conducted in the wad medani hospital, in an area of central sudan that is characterised by unstable malarial transmission. its aims were to investigate the roles and interactions of cortisol, prolactin, interferon-gamma (ifn-gamma), interleukin-4 (il-4) and interleukin-10 (il-10) in pregnant women wit ... | 2009 | 19208295 |
| the spatial-temporal clustering of plasmodium falciparum infection over eleven years in gezira state, the sudan. | malaria infection and disease exhibit microgeographic heterogeneity which if predictable could have implications for designing small-area intervention. here, the space-time clustering of plasmodium falciparum infections using data from repeat cross-sectional surveys in gezira state, a low transmission area in northern sudan, is investigated. | 2010 | 20565854 |
| frequency distribution of antimalarial drug resistance alleles among plasmodium falciparum isolates from gezira state, central sudan, and gedarif state, eastern sudan. | in 2004, sudan adopted artesunate + sulfadoxine/pyrimethamine (sp) combination as the first-line drug, in response to the high level of falciparum resistance to antimalarials. in 2007, a molecular study on antimalarial resistance linked genes, pfcrt, pfmdr1, pfdhfr, pfdhps, and pfatpase6, was conducted on 198 isolates from central and eastern sudan. we observed a high frequency of point mutations at almost all loci analyzed, mainly of pfcrt 76t (72.7%), pfdhfr 51i (75.3%), and pfdhfr 108n (72.7% ... | 2010 | 20682863 |
| a perspective of the epidemiology of malaria and anaemia and their impact on maternal and perinatal outcomes in sudan. | both malaria and anaemia have adverse effects on maternal and perinatal outcomes. thus there is an urgent need to investigate the co-epidemiology of malaria and anaemia and their combined impact on maternal and perinatal outcomes in the different regions of sudan. | 2011 | 21389586 |
| hypoglycaemia and severe plasmodium falciparum malaria among pregnant sudanese women in an area characterized by unstable malaria transmission. | abstract: background: pregnant women are more susceptible to severe plasmodium falciparum malaria, which can lead to poor maternal and fetal outcomes. few data exist on the epidemiology of severe p. falciparum malaria in pregnant women. a hospital-based study was carried out to assess the pattern of severe p. falciparum malaria among pregnant women at the kassala and medani maternity hospitals, which are located in areas of unstable malaria transmission, in eastern and central sudan, respectivel ... | 2011 | 21605445 |
| fluorescence microscope (cyscope) for malaria diagnosis in pregnant women in medani hospital, sudan. | accuracy of diagnosis is the core for malaria control. although microscopy is the gold standard in malaria diagnosis, its reliability is largely dependent on user skill. we compared performance of cyscope fluorescence microscope with the giemsa stained light microscopy for the diagnosis of malaria among pregnant women at medani hospital in central sudan. the area is characterized by unstable malaria transmission. | 2011 | 21943212 |
| effect of quinine therapy on plasma glucose and plasma insulin levels in pregnant women infected with plasmodium falciparum malaria in gezira state. | to determine if quinine has a metabolic effect during treatment of severe or complicated malaria, we studied its effects on plasma glucose and plasma insulin levels in 150 pregnant women with malaria referred to madani maternity teaching hospital, gezira state and 50 healthy pregnant controls. levels were determined at baseline (day 0) before the start of quinine treatment, after 2 days of treatment (2 hours after the 4th dose) and after 7 days of treatment (day 8). there was a statistically sig ... | 2011 | 22259921 |