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[effectiveness of combined therapies using two types of peginterferon and ribavirin in treating chronic hepatitis c virus genotypes 1b/6a infections].to explore the effectiveness of a combined therapy using two types of peginterferon (peg-ifn) and ribavirin in treating chronic hepatitis c virus (hcv) genotypes 1b/6a infections.201020602887
genotyping hepatitis c virus isolates from spain, brazil, china, and macau by a simplified pcr method.an improved and simplified method of genotyping was developed for classifying hepatitis c virus (hcv) isolates into the five common genotypes, i.e., i/1a, ii/1b, iii/2a, iv/2b, and v/3a, by pcr with genotype-specific primers deduced from the core gene. sense and antisense primers, specific for each of the five common genotypes, were designed by comparison of 319 core gene sequences from hcv isolates of various genotypes from genetic groups 1 to 9. in the first round of pcr, a sequence of 433 bp ...19968880482
survey of type 6 group variants of hepatitis c virus in southeast asia by using a core-based genotyping assay.previous surveys of the prevalences of genotypes of hepatitis c virus (hcv) in different populations have often used genotyping assays based upon analysis of amplified sequences from the 5' noncoding region (5'ncr), such as restriction fragment length polymorphism (rflp) or hybridization with type-specific probes (e.g., innolipa). although highly conserved, this region contains several type-specific nucleotide polymorphisms that allow major genotypes 1 to 6 to be reliably identified. recently, h ...19968789027
antibodies to hepatitis c virus in blood donors and polytransfused patients of macau (southeast china) 19937504374
complete coding sequence of hepatitis c virus genotype 6a.hepatitis c virus (hcv) genotype 6a is found in a restricted part of south east asia, including hong kong, macau and vietnam. we determined the full length coding sequence of a type 6a isolate (euhk2) obtained from a hong kong blood donor. the sequence of euhk2 contained a single open reading frame coding for a polyprotein of 3018 amino acids, within the range of 3008 to 3037 for other hcv genotypes. the full length sequence of euhk2 showed 30.3%-32.9% nucleotide (24.3%-29.4% amino acid) sequenc ...19979177282
methadone maintenance treatment experience in macao--prospective follow-up for initial 4.5 years.the initiation of the first methadone maintenance treatment program (mmt) in macao was founded in collaboration between mmt clinics in the usa and israel. all patients admitted into treatment between october 2005 and october 2008 were prospectively followed through march 2010. of the 163 patients, 81% were male, the mean age on admission was 39.5 (sd = 10.2). seventy-three percent (n = 119) were hepatitis c sera positive, and 4.9% (n = 8) were hiv sera positive. one-year treatment retention rate ...201324377170
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