plasmid encoded multi-drug resistance in salmonella typhi from pakistan.twenty-five isolates of salmonella typhi made from cases of typhoid fever during 1990-1991 in rawalpindi and islamabad, were examined. all isolates were resistant to chloramphenicol, ampicillin, tetracycline, streptomycin, sulphamethoxazole and trimethoprim, but were sensitive to nalidixic acid, ofloxacin, ciprofloxacin, cefuroxime and cefotaxime. a single large 98 mda plasmid was identified in all the isolates. the plasmid was self-transferable and encoded resistance to chloramphenicol, ampicil ...19938250628
characterization of multi-drug resistant salmonella typhi isolated from pakistan.thirty-nine strains of salmonella typhi, isolated in 1995 from four districts in pakistan, rawalpindi, islamabad, kharian and jehlem, were catalogued and examined. chromosomal dna from each isolate was digested with xbai restriction endonuclease and subjected to pulsed-field gel electrophoresis. three clonal variants comprising of 17-19 dna fragments were identified. antibiotic susceptibility testing identified that 37 of the s. typhi were resistant to chloramphenicol, trimethoprim and ampicilli ...200010722124
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