Publications

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nonspecific vaginitis and other genital infections in three clinic populations.nonspecific vaginitis was present in 37% of 40 patients attending the special urology (sexually transmitted disease) clinic at the victoria general hospital, in 23% of 75 patients attending the family planning clinic, and in 23% of 13 patients attending the prenatal clinic at the grace maternity hospital in halifax, nova scotia. the mean prevalence was 27%. subjective complaints of vaginal odor were significantly associated with nonspecific vaginitis (p less than .001), but symptoms of vaginal d ...19836648745
linkage disequilibrium mapping of the nova scotia variant of niemann-pick disease.niemann-pick type d (npd) disease is a severe degenerative disorder of the nervous system characterized by the accumulation of tissue cholesterol and sphingomyelin. because of a founder effect, it is unusually common in southwestern nova scotia, canada. we have confirmed that almost all patients from 20 affected sibships descended on both sides from a small group of acadians who settled in this region in about the year 1767. previously using classic linkage analysis of this large kindred, we def ...199910361985
shewanella halifaxensis sp. nov., a novel obligately respiratory and denitrifying psychrophile.indigenous bacteria found in the sediment of the emerald basin (depth of 215 m, atlantic ocean) located offshore of halifax harbour (nova scotia, canada) were previously found to be able to degrade the explosive compound hexahydro-1,3,5-trinitro-1,3,5-triazine (rdx). in the present study, a novel obligately respiratory, denitrifying and rdx-mineralizing bacterium, designated strain haw-eb4(t), was isolated from the marine sediment. this bacterium utilized peptone, yeast extract, casamino acids, ...200616403888
shewanella canadensis sp. nov. and shewanella atlantica sp. nov., manganese dioxide- and hexahydro-1,3,5-trinitro-1,3,5-triazine-reducing, psychrophilic marine bacteria.two strains belonging to the genus shewanella, haw-eb2(t) and haw-eb5(t), were isolated previously from marine sediment sampled from the atlantic ocean, near halifax harbour in canada, for their potential to degrade explosive hexahydro-1,3,5-trinitro-1,3,5-triazine (rdx). in the present study, strains haw-eb2(t) and haw-eb5(t) were found to display high 16s rrna gene sequence similarity (90-99.5 %) to species of shewanella, but their gyrb sequences were significantly different from each other an ...200717766891
isolation and optimisation of the oleaginous yeast sporobolomyces roseus for biosynthesis of (13)c isotopically labelled 18-carbon unsaturated fatty acids and trans 18:1 and 18:2 derivatives through synthesis.an oleaginous and psychrotrophic strain (f38-3) of sporobolomyces roseus kluyver & van niel was isolated from a salt marsh environment in nova scotia, canada following a screening program to select for high producers of 18-carbon unsaturated fatty acids. fatty acid production was characterised as a function of temperature at 20 g glucose l(-1), and optimal yields were obtained at 14°c, achieving 5.7 g dw biomass and 39.2% total fatty acids by dry weight, with 18:1, 18:2 and 18:3 all-cis fatty ac ...201121809096
molecular and functional analysis of three fatty acyl-coa reductases with distinct substrate specificities in copepod calanus finmarchicus.the marine copepod calanus finmarchicus constitutes the substantial amount of biomass in the arctic and northern seas. it is unique in that this small crustacean accumulates a high level of wax esters as carbon storage which is mainly comprised of 20:1n-9 and 22:1n-11 alcohols (alc) linked with various kinds of fatty acids, including n-3 polyunsaturated fatty acids. the absence of 20:1n-9 alc and 22:1n-11 alc in diatoms and dinoflagellates, the primary food sources of copepods, suggests the exis ...201121918929
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