Publications

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immunogenicity and safety of a novel yeast hansenula polymorpha-derived recombinant hepatitis b candidate vaccine in healthy adolescents and adults aged 10-45 years.the aim was to determine whether the immunogenicity of an investigational hepatitis b vaccine (sphb) is at least as high as that of a licensed control vaccine, engerix b, and to evaluate its safety before inclusion in new pediatric combination vaccines. two randomized, controlled, blind-observer, phase 3 trials were performed: one in argentina (344 participants aged 10-15 years, 10 microg hbsag/dose) and one in uruguay (344 participants aged 16-45 years, 20 microg hbsag/dose). both vaccines were ...201020189492
[isolation of atmospheric-nitrogen-fixing spirilla from the waters of the paraná delta and other rivers].seventeen strains of spirillum-like organisms (2) were isolated from the parana delta and other rivers (table 1), using the following medium: 0.5% malic acid; 0.4% koh; 0.5% k2hpo4; 0.005% yeast extract; ph was adjusted to 7 with koh and 0.15% agar. the organisms produced a white, dense and sub-superficial pellicle in this medium, and streaking them on plates, single colonies could be isolated. they were easily recognized thanks to the congo red added to the medium, because the bacteria, as it h ...19846400725
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