Publications

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hogg1 ser326cys polymorphism and lung cancer susceptibility.the human homologue of the yeast ogg1 gene, hogg1, has been cloned, and its genetic structure has been determined. several polymorphisms in the hogg1 gene were detected in the japanese populations, and among them, the ser-cys polymorphism at codon 326 has been shown to have a functional difference in complementation of mutant escherichia coli that is defective in the repair of 8-hydroxyguanine. activity in the repair of 8-hydroxyguanine is greater in hogg1-ser326 protein than in hogg1(326) prote ...199910744126
carboxydobrachium pacificum gen. nov., sp. nov., a new anaerobic, thermophilic, co-utilizing marine bacterium from okinawa trough.a new anaerobic, thermophilic, co-utilizing marine bacterium, strain jmt, was isolated from a submarine hot vent in okinawa trough. cells of strain jmt were non-motile thin straight rods, sometimes branching, with a cell wall of the gram-positive type, surrounded with an s-layer. chains of three to five cells were often observed. the isolate grew chemolithotrophically on co, producing equimolar quantities of h2 and co2 (according to the equation co+h2o-->co2+h2) and organotrophically on peptone, ...200111211251
thermosipho japonicus sp. nov., an extremely thermophilic bacterium isolated from a deep-sea hydrothermal vent in japan.a novel barophilic, extremely thermophilic bacterium was isolated from a deep-sea hydrothermal vent chimney at the iheya basin, in the okinawa area, japan. the cells were found to be rod shaped and surrounded by a sheath-like outer structure; the organism did not possess flagella and was not motile. growth was observed between 45 degrees and 80 degrees c (optimum, 72 degrees c, 45 min doubling time), ph 5.3 and 9.3 (optimum, ph 7.2-7.6), 6.6 and 79g/l sea salts (optimum, 40g/l), and 0.1 and 60mp ...200010741832
pyrococcus horikoshii sp. nov., a hyperthermophilic archaeon isolated from a hydrothermal vent at the okinawa trough.a hyperthermophilic, anaerobic archaeon was isolated from hydrothermal fluid samples obtained at the okinawa trough vents in the ne pacific ocean, at a depth of 1395m. the strain is obligately heterotrophic, and utilizes complex proteinaceous media (peptone, tryptone, or yeast extract), or a 21-amino-acid mixture supplemented with vitamins, as growth substrates. sulfur greatly enhances growth. the cells are irregular cocci with a tuft of flagella, growing optimally at 98 degrees c (maximum growt ...19989672687
livestock wastes as a source of estrogens and their effects on wildlife of manko tidal flat, okinawa.the manko tidal flat in the southern part of okinawa island is an important visiting and wintering area for migratory birds and was added to the ramsar convention register of wetlands in 1999. this area used to be an inlet extending to the inner part of naha port, but recent reclamation projects have restricted its connection to the east china sea. as is typical in rural regions of subtropical islands, the inhabitants in the manko basin raise livestock, especially pigs, without employing suffici ...200312787611
isolation and characterization of awamori yeast mutants with l-leucine accumulation that overproduce isoamyl alcohol.awamori shochu is a traditional distilled alcoholic beverage made from steamed rice in okinawa, japan. although it has a unique aroma that is distinguishable from that of other types of shochu, no studies have been reported on the breeding of awamori yeasts. in yeast, isoamyl alcohol (i-amoh), known as the key flavor of bread, is mainly produced from α-ketoisocaproate in the pathway of l-leucine biosynthesis, which is regulated by end-product inhibition of α-isopropylmalate synthase (ipms). here ...201525060730
exilispira thermophila gen. nov., sp. nov., an anaerobic, thermophilic spirochaete isolated from a deep-sea hydrothermal vent chimney.a novel thermophilic, anaerobic bacterium, strain rasen(t), was isolated from a deep-sea hydrothermal vent chimney sample collected in the iheya north field, okinawa trough, japan, at a water depth of 982 m. the cells were motile, gram-negative and helical with hooked ends, 0.23-0.28x15-27 microm in size with an approximate wavelength of 1.1-1.5 microm. growth of the strain was observed at 37-60 degrees c (optimum 50 degrees c), in 2.5-3.5 % (w/v) nacl (optimum 2.5-3 % nacl) and at ph 6.0-7.5 (o ...200818842837
sulfurivirga caldicuralii gen. nov., sp. nov., a novel microaerobic, thermophilic, thiosulfate-oxidizing chemolithoautotroph, isolated from a shallow marine hydrothermal system occurring in a coral reef, japan.novel thermophilic bacteria, designated strains vw1 and mm1(t), were isolated from hydrothermal fluid and microbial mat samples, respectively, collected from a shallow marine hydrothermal system (water depth 22 m) occurring in coral reefs off taketomi island, okinawa, japan. cells of the two novel strains were motile rods with a single polar flagellum in the exponential growth phase. in a medium that included elemental sulfur, cells of the two strains became non-motile with oval to spherical cel ...200616902032
sulfurimonas paralvinellae sp. nov., a novel mesophilic, hydrogen- and sulfur-oxidizing chemolithoautotroph within the epsilonproteobacteria isolated from a deep-sea hydrothermal vent polychaete nest, reclassification of thiomicrospira denitrificans as sulfurimonas denitrificans comb. nov. and emended description of the genus sulfurimonas.a novel mesophilic bacterium, strain go25(t), was isolated from a nest of hydrothermal vent polychaetes, paralvinella sp., at the iheya north field in the mid-okinawa trough. cells were motile short rods with a single polar flagellum. growth was observed between 4 and 35 degrees c (optimum 30 degrees c; 13-16 h doubling time) and between ph 5.4 and 8.6 (optimum ph 6.1). the isolate was a facultatively anaerobic chemolithoautotroph capable of growth using molecular hydrogen, elemental sulfur or t ...200616901999
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