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higher rates of streptococcal colonization among children in the pacific rim region correlates with higher rates of group a streptococcal disease and sequelae.group a streptococcal (gas) pharyngeal colonization rates were determined among 1061 asymptomatic students in hawaii and american samoa where acute rheumatic fever rates are high. all gas isolates were emm sequence typed. although pharyngeal colonization rates were low in hawaii (3.4%), pacific islander children had significantly higher colonization rates (5.7% vs. 1.2% in other ethnic groups, p <0.05). the colonization rate was higher in american samoa (13%). few emm types that were infrequentl ...201019681949
streptococcal emm types in hawaii: a region with high incidence of acute rheumatic fever.the clinical epidemiology of group a streptococcal (gas) infections in hawaii seems different from that in the continental united states with frequent skin infections and endemically high rates of acute rheumatic fever (arf).200919057463
acute rheumatic fever in american samoa.acute rheumatic fever is common among samoans in hawaii. during 2 visits to evaluate the magnitude of rheumatic fever problem among samoans in american samoa, we identified 148 patients with rheumatic fever on penicillin prophylaxis. retrospective chart reviews were done showing possible delays in diagnosis of acute rheumatic fever.200718043459
acute post-streptococcal glomerulonephritis in children of french polynesia: a 3-year retrospective study.the aim of this study was to define the current demographic, clinical and prognostic characteristics of acute post-streptococcal glomerulonephritis (apsgn) in french polynesia and to compare these features with those of other populations. fifty children, all of whom were <15 years old and had been admitted to the territorial hospital of papeete for apsgn between january 2005 and december 2007, were retrospectively enrolled in the study. diagnostic criteria were microscopic or macroscopic haematu ...201019876655
life-threatening cellulitis after traditional samoan tattooing.traditional samoan tattooing is a significant and valued cultural practice. any tattooing carries a risk of complications, including the potential for serious bacterial infection. we discuss the complex nature of the public health investigation into two cases of serious bacterial infection following traditional tattooing occurring in the same region in new zealand within a six-week period.201121299697
characterization of a community cluster of group a streptococcal invasive disease in maui, hawaii.a community cluster of severe group a streptococcal skin infections occurred in maui, hawaii with 3 fatal cases of necrotizing fasciitis in 2002. emm types 1, 12, 58, 74, 85 and 109 were identified from 8 patients. emm types 74 and 109 have not been previously described in the united states according to the centers for disease control and prevention database. the identification of uncommon emm types suggested that group a streptococcal sero-types in hawaii are different from those in the contine ...200415247611
group a streptococcal isolates temporally associated with acute rheumatic fever in hawaii: differences from the continental united states.the annual incidence of acute rheumatic fever (arf) in hawaii has remained several times higher than that in the continental united states, particularly among ethnic polynesians. the emm types of streptococcus pyogenes that are associated with this nonsuppurative complication have, to our knowledge, not been previously reported in hawaii.200717599299
anti-microbial activity and anti-complement activity of extracts obtained from selected hawaiian medicinal plants.selected plants having a history of use in polynesian traditional medicine for the treatment of infectious disease were investigated for anti-viral, anti-fungal and anti-bacterial activity in vitro. extracts from scaevola sericea, psychotria hawaiiensis, pipturus albidus and eugenia malaccensis showed selective anti-viral activity against herpes simplex virus-1 and 2 and vesicular stomatitis virus. aleurites moluccana extracts showed anti-bacterial activity against staphylococcus aureus and pseu ...19958786654
infectious complications of traditional samoan tattooing. 200516230224
molecular epidemiologic comparison of 2 unusual clusters of group a streptococcal necrotizing fasciitis in hawaii.two clusters of necrotizing fasciitis (nf) due to group a streptococcus (gas) were identified on the hawaiian islands of kauai and maui during 1997 and 2002, respectively. the emm gene sequence types and the pulsed-field gel electrophoresis patterns were determined for 6 isolates recovered from patients with nf and for 116 isolates recovered from patients with temporally associated community-acquired gas infection. no predominant emm type was identified, and the emm types of 64 (52.5%) of the is ...200515909276
skin infections of the limbs of polynesian children.the aim of this study was to obtain information regarding the incidence of cellulitis or cutaneous abscess in children of polynesian ethnicity (including new zealand maori), and to calculate the relative risk increase versus other ethnicities.200415107869
emergence of erythromycin- and clindamycin-resistant streptococcus pyogenes emm 90 strains in hawaii.we identified 12 erythromycin- and clindamycin-resistant emm 90 group a streptococcus (gas) isolates during a retrospective invasive disease survey in hawaii. a comparison with 20 type-matched isolates showed all resistant isolates to be emm 90.4b with the constitutive or inducible macrolide-lincosamide-streptogramin b resistance phenotype (cmls(b) or imls(b)). all isolates had the same pulsed-field gel electrophoresis (pfge) pattern, suggesting clonal spread.201021068284
penicillin tolerance and erythromycin resistance of group a beta-hemolytic streptococci in hawaii and the philippines.penicillin remains the drug of choice for the treatment of streptococcal pharyngitis, with erythromycin as an alternative drug for individuals who cannot take penicillin. two areas of concern in the management of streptococcal pharyngitis are (1) the prevalence of penicillin-tolerant group a beta-hemolytic streptococci reported in recent studies and (2) the high prevalence of erythromycin resistance in some geographic areas. we tested 305 isolates of group a beta-hemolytic streptococci from hawa ...19902184661
throat streptococcal survey in school children, hawaii, 1976-80. 19826757180
pyomyositis. report of 18 cases in hawaii.eighteen patients with pyomyositis were seen at a large hospital in hawaii. most were healthy young men or boys, and eight had never traveled abroad. fever, muscle pain and swelling, and leukocytosis were common, but only seven had erythema or fluctuance. a single large muscle was infected in 14, and two to three muscles were infected in the others. pyomyositis mimicked cellulitis, muscle hematoma, thrombophlebitis, appendicitis, and neoplasm. staphylococcus aureus was found in 13, and streptoco ...19846476991
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