Publications

on the reportability of nontuberculous mycobacterial disease to public health authorities.	nontuberculous mycobacteria (ntm) are environmental pathogens that are an increasingly common cause of pulmonary and extrapulmonary disease. electronic laboratory-based reporting is a straightforward mechanism for identifying ntm infections and for monitoring trends in disease. oregon was the first state to make ntm reportable, although at this time the reporting requirement is limited to extrapulmonary infection. this has assisted authorities in detecting outbreaks and healthcare-related infect ...	2017	27997817
disseminated nontuberculous mycobacteria in hiv-infected patients, oregon, usa, 2007-2012.	we determined disseminated nontuberculous mycobacteria incidence in the hiv-infected population of oregon, usa, during 2007-2012 by using statewide laboratory surveillance. we identified 37 disseminated nontuberculous mycobacteria cases among 7,349 patients with median annual incidence of 110/100,000 hiv person-years and the highest incidence in those with cd4 counts <50 cells/mm(3) (5,300/100,000 person-years).	2017	28221103
surveillance of extrapulmonary nontuberculous mycobacteria infections, oregon, usa, 2007-2012.	limited data are available describing extrapulmonary nontuberculous mycobacteria (ntm) infections in the general population. we describe results from statewide population-based laboratory surveillance in oregon, usa, during 2007-2012. we defined a case of extrapulmonary ntm infection as >1 isolate from skin/soft tissue, disseminated sites, lymph node, joint, or other sites. the annual incidence of extrapulmonary ntm infection (other than mycobacterium gordonae) was stable, averaging 1.5 cases/10 ...	2017	28930014
mycobacterium talmoniae sp. nov., a slowly growing mycobacterium isolated from human respiratory samples.	a novel slowly growing, non-chromogenic species of the class actinobacteria was isolated from a human respiratory sample in nebraska, usa, in 2012. analysis of the internal transcribed spacer sequence supported placement into the genus mycobacterium with high sequence similarity to a previously undescribed strain isolated from a patient respiratory sample from oregon, usa, held in a collection in colorado, usa, in 2000. the two isolates were subjected to phenotypic testing and whole genome seque ...	2017	28809146
implications of pcr and elisa results on the routes of bulk-tank contamination with mycobacterium avium ssp. paratuberculosis.	mycobacterium avium ssp. paratuberculosis (map), the etiologic agent of johne's disease in dairy cattle, may enter the bulk tank via environmental contamination or direct excretion into milk. traditionally, diagnostics to identify map in milk target either map antibodies (by elisa) or the organism itself (by culture or pcr). high elisa titers may be directly associated with excretion of map into milk but only indirectly linked to environmental contamination of the bulk tank. patterns of bulk-mil ...	2016	26686723
population-based incidence of pulmonary nontuberculous mycobacterial disease in oregon 2007 to 2012.	pulmonary nontuberculous mycobacteria (ntm) disease is a chronic, nonreportable illness, making it difficult to monitor. although recent studies suggest an increasing prevalence of ntm disease in the united states, the incidence and temporal trends are unknown.	2015	25692495
pulmonary nontuberculous mycobacterial disease prevalence and clinical features: an emerging public health disease.	respiratory specimens with nontuberculous mycobacteria (ntm) are increasingly common; however, pulmonary disease prevalence is unknown.	2010	20508209
surveys for disease agents in introduced elk in arkansas and kentucky.	surveys for disease agents were conducted in introduced free-ranging elk (cervus elaphus nelsoni) in arkansas and kentucky. elk had been captured in colorado and nebraska and released in arkansas during 1981-1985. from 1997 through 2002 elk were captured in arizona, kansas, north dakota, new mexico, oregon, and utah and released in southeastern kentucky. specimens were collected from 170 hunter-killed elk in arkansas during 1998-2006, and 44 elk in kentucky during 2001-2004. significant findings ...	2010	20090032
nontuberculous mycobacterial disease prevalence and risk factors: a changing epidemiology.	nontuberculous mycobacteria (ntm) are important human pathogens, yet little is known about disease prevalence in the united states. reports suggest prevalence has increased, particularly in women, but population-based data to substantiate this are lacking. we sought to estimate ntm disease prevalence in oregon, and describe disease by site, species, and patient demographic characteristics.	2009	19911942