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apoptosis, production of mmp9, vegf, tnf-alpha and intracellular growth of m. tuberculosis for different genotypes and different pks5/1 genes.a previous study of is6110 rflp and spoligotyping of m. tuberculosis isolates from 152 thai patients with tuberculous meningitis revealed a significantly higher percentage (57%) of the beijing genotype as compared to isolates obtained from pulmonary tuberculosis. we postulated that the m. tuberculosis beijing genotype is likely to be more virulent than others.201122053594
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