Publications

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antimicrobial resistance in campylobacter spp. isolated from ontario sheep flocks and associations between antimicrobial use and antimicrobial resistance.the objectives of this study were to determine the prevalence of antimicrobial resistance (amr) in faecal campylobacter spp. from lambs and adult sheep and associations between antimicrobial use (amu) and amr. a total of 275 faecal samples collected during initial and final visits from 51 sheep flocks, including one feedlot, across southern ontario were tested for the presence of campylobacter spp. campylobacter jejuni was detected in 52% (143/275) of the faecal samples, campylobacter coli in 7% ...201222273455
rates and determinants of antimicrobial use, including extra-label, on ontario sheep farms.few antimicrobials are licensed for use in sheep in canada, and the range of indications is narrow. treatment in an "extra-label" manner may be ineffective. in addition, potentially harmful drug residues in food-animal products and antimicrobial resistance in bacteria may be associated with extra-label drug use (eldu). no data had been documented on drug use, specifically antimicrobial use (amu), in ontario sheep, although it was thought that much use was extra-label. this study investigated amu ...201121461189
evaluation of a british computer model to simulate gastrointestinal nematodes in sheep on canadian farms.with increasing levels of anthelmintic resistance worldwide and a growing demand to produce more organic products, utilisation of control strategies for gastrointestinal nematodes (gin) that minimize the use of anthelmintics becomes even more important. this study evaluated the farm-level performance of an existing predictive sheep parasite model from the united kingdom (uk), using canadian data. the uk model simulates the epidemiology of three major gin species of interest (teladorsagia spp., h ...201020863622
prevalence and distribution of gastrointestinal nematodes on 32 organic and conventional commercial sheep farms in ontario and quebec, canada (2006-2008).in order to characterize the epidemiology of sheep gastrointestinal nematodes in organic and conventional flocks in canada, a longitudinal study was carried out from may 2006 to march 2008 on 32 purposively selected farms in ontario (on) and quebec (qc): 8 certified organic (co), 16 non-certified organic (nco), and 8 conventional (c) farms. on each farm, 10 ewes and 10 female lambs were selected. farm visits were undertaken monthly during the grazing season, and twice in the winter. at each visi ...201020236769
characteristics of drug use on sheep farms in ontario, canada.this study examined characteristics of the use of drugs, especially antimicrobials, on ontario sheep farms. forty-nine sheep farms participated in a 12-month prospective study. producers documented treatment events during the study period and drug use data from the records were summarized. the most frequently used drugs of the 15 drug categories used by producers belonged to the following categories: antimicrobial (40.7%, n=2710), vitamin/mineral (12.0%), and biological (11.1%). short-acting pen ...201021358930
trial of essiac to ascertain its effect in women with breast cancer (tea-bc).breast cancer is a major cause of morbidity, mortality, and medical expenditures among women in canada. essiac (resperin canada limited, waterloo, ontario, canada), a blend of at least four herbs (burdock root [arctium lappa], indian rhubarb [rheum palmatum], sheep sorrel [rumex acetosella], and the inner bark of slippery elm [ulmus fulva or u. rubra]), has become one of the more popular herbal remedies for breast-cancer treatment, secondary prevention, improving quality of life, and controlling ...200617212569
survey of the status of copper, interacting minerals, and vitamin e levels in the livers of sheep in ontario.livers from cull ewes and market lambs raised in ontario were obtained to determine the status of specific minerals and vitamin e. values for copper (cu), iron (fe), manganese (mn), and zinc (zn) obtained by atomic absorption and inductively coupled plasma--atomic emission spectroscopy (icp-aes) were found to be statistically different but sufficiently biologically similar to allow the use of icp-aes for screening groups of samples for deficient or toxic levels of those minerals. toxic levels of ...200314664352
retrospective study of toxic metal analyses requested at a veterinary diagnostic toxicology laboratory in ontario (1990-1995).during the 5-year period from january 1, 1990, to december 31, 1995, 887 diagnoses of metal toxicosis in domestic animals and wild birds were documented at the veterinary laboratory services branch of the ontario ministry of agriculture, food and rural affairs. most of these cases involved cattle, sheep, and birds. lead toxicosis was diagnosed in 399 cases, copper toxicosis in 387, zinc toxicosis in 49, mercury toxicosis in 44, iron toxicosis in 4, and selenium in 4 cases. trends in species affe ...19989442951
eperythrozoonosis in sheep. 19969111697
forensic application of repetitive dna markers to the species identification of animal tissues.highly repetitive dna markers have been used for determining the species origin of animal tissues in cases of illegal commercialization and poaching of game animals. this approach has been used in cases involving white-tailed deer (odocoileus virginianus), moose (alces alces) and black bear (ursus americanus). digesting the dna with various restriction enzymes, agarose electrophoresis and staining with ethidium bromide revealed unique banding patterns for each species. these patterns have been u ...19948195749
the seroprevalence of maedi-visna in ontario sheep flocks and its relationship to flock demographics and management practices.the objectives of this study were to describe the serological prevalence of maedi-visna in a sample of ontario sheep flocks, and to identify management and demographic variables that were associated with seroprevalence for maedi-visna. a sample of 103 sheep flocks in ontario was randomly selected from those flocks participating in the red meat plan. the owners of these flocks were surveyed regarding management procedures on their farms, and blood samples were taken from a random sample of ewes i ...19948044757
the seroprevalence of coxiellosis (q fever) in ontario sheep flocks.a serological survey for coxiella burnetii was undertaken on a randomly selected population of 103 ontario sheep flocks. twenty-two flocks had at least one positive ewe; seven flocks had two or more reactors. the positive flocks were geographically clustered northwest of guelph. crutch-clipping of the ewe's wool prior to lambing, and total confinement housing at lambing in winter and spring seemed to lower the probability of seroreactivity of the flock (p less than 0.05). the study suggests that ...19911884293
immunomodulation in c57bl/6 mice following consumption of halogenated aromatic hydrocarbon-contaminated coho salmon (oncorhynchus kisutch) from lake ontario.this report describes studies designed to assess the immunomodulatory effects associated with the consumption of coho salmon containing halogenated aromatic hydrocarbons (hahs) and other compounds naturally bioaccumulated from lake ontario. diets containing 33% coho salmon from lake ontario or the pacific ocean were fed to juvenile c57bl/6 mice for 2-4 mo. following 60 d, the mice that consumed lake ontario salmon had reduced igm, igg, and iga plaque-forming cell responses to sheep erythrocytes. ...19892527307
monitoring wood shaving litter and animal products for polychlorophenols residues, ontario, canada, 1978-1986. 19883130916
factors associated with productivity in canadian sheep flocks.a mail survey of canadian sheep flocks registered on the record of performance program was conducted, and the association of management practices and diseases with productivity was studied using multiple regression techniques. the relationships between management practices and diseases of lambs which were associated with production were also investigated using discriminant analysis. flocks in the maritimes had a lower average flock productivity than those in ontario-quebec and the western provin ...19873567750
q fever: hazard from sheep used in research.the recent recognition that q fever is endemic in ontario and the known occupational risk of q fever to research personnel working with sheep prompted a study to determine the prevalence of antibodies to the causative organism, coxiella burnetti, in animals and staff at a toronto animal research institute. of 37 sheep 34 (92%) were found to be seropositive--that is, to have a titre of complement-fixing antibody to the phase ii antigen of 1:8 or greater. of 331 staff members tested, 18% were foun ...19846704847
listeria monocytogenes infections in canada.since its first isolation by murray in 1926 listeria monocytogenes has become recognized as a significant pathogen occurring worldwide and involving a wide range of wild and domestic animals including man. the first confirmed human listeriosis case in canada was published by stoot in 1951. a later survey based on records maintained at the laboratory centre for disease control, ottawa showed 101 cases detected over a 21 year period in nine provinces. the overall mortality was 30%. the most freque ...19846442654
approaches to immunization of infants and young children against gastroenteritis due to rotaviruses.recent studies have shown that in developed countries rotaviruses are the single most important etiologic agents of acute gastroenteritis that requires hospitalization of infants and young children. although deaths from gastroenteritis are, in general, infrequent in the developed countries, an effective rotavirus vaccine would clearly be of benefit to reduce the heavy toll of morbidity from gastroenteritis due to rotavirus. in the developing countries the impact of diarrheal diseases is staggeri ...19806251528
the prevalence of serum antibodies to toxoplasma gondii in ontario mammals.the prevalence of seropositive reactions to toxoplasma gondii was studied in farm animals, companion animals, wild rodents and birds. of the animals tested, 17% of cattle, 65% of sheep, 45% of pigs, 9% of horses, 33% of dogs and 20% of cats were seropositive by the sabin-feldman dye test. in addition 11% of mice (mus musculus), 5% of deer mice (peromyscus), 3% of rats (rattus norvegicus) and less than 2% of sparrows (passer domestcus) were seropositive. all samples from short-tailed field mice ( ...1978667705
the gross and histopathologic lesions of maignant catarrhal fever in three captive sika deer (cervus nippon) in southern ontario.the gross and histopathologic lesions of three captive sika deer (cervus nippon) with malignant catarrhal fever are described. lesions included those of the head and eye form and the more commonly described peracute form. one deer had been exposed to a wildebeeste (connochaetes gnou) and the other two to domestic sheep.1977557117
an immunoprecipitin study of the incidence of influenza a antibodies in animal sera in the ottawa area.a survey of over 600 'normal' sera from 14 animal species by immunoprecipitin tests in cellulose acetate using viron antigens revealed a high incidence of precipitating activity against a broad range of influenza a virus strains, particularly a2hhong kong/1/68 and /pr8. however, serum treatments trypsin-heat-periodate, naio4, v. cholerae receptor-destroying enzyme (rde), or kaolin eliminated most precipitating activity, which suggests that it was due to "non-specific" inhibitors of influenze vir ...1975167931
a survey of vertebral abscesses in domestic animals in ontario. 19751131789
some analyses of exsheathing fluid from infective haemonchus contortus larvae from ontario. 19744217323
drug resistance among pathogenic bacteria from animals in ontario.prevalence of antimicrobial drug resistance among over 3000 clinical isolates of animal pathogens in ontario during 1971-72 has been studied. a high number of multiple resistance patterns is prevalent among members of enterobacteriaceae, especially escherichia coli and salmonella typhimurium. the most common resistance pattern among bovine strains was against not less than six drugs in common use. among different animal species the bovine population was found to be the source of a high percentag ...19744277443
parasitisms in domesticated animals in ontario. i. ontario veterinary college records 1965-70. 19734688875
morphological types in haemonchus contortus (nematoda) populations in ontario sheep. 19734778357
disease trends in domestic animals and poultry in ontario 1971-72. 19734711498
isolation of listeria monocytogenes from brain specimens of domestic animals in ontario. 19715005795
a note on selenium contents of two leguminous forage species collected in ontario and the possible incidence on selenium-responsive diseases. 19695816710
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