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antineoplastic agents. 488. isolation and structure of yukonin from a yukon territory fungus.cancer cell line bioassay-guided separation of an extract from a yukon territory fungus resulted in the isolation of a new c(16)-terpene dilactone designated yukonin (1) accompanied by two previously known, structurally related constituents (2 and 3). the structure of each was determined by x-ray crystallographic analysis. dilactone 2 was found to correspond to ll-z1271alpha isolated from fungi in the genera oidiodendron, acrostalagmus, and holwaya, while dilactone 3 had earlier been prepared by ...200312608865
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