Publications

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[antimicrobial activity of various algae of the panamanian atlantic coast].the methanolic extracts in 5 of 7 alagae from the atlantic coast of panama: caulerpa racemosa, halimeda opuntia, gelidiela acerosa, laurencia papillosa y acanthophora spicifera, showed antimicrobial activity against staphylococcus aureus and bacillus subtilis in a concentration of 50 mg/ml by the cylinder plate method. none of the algae studies showed activity against escherichia coli, pseudomonas aeruginosa, aspergillus niger and candida albicans. the content of agar in acanthophora spicifera w ...19912024058
structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly.hectochlorin (1) was isolated from marine isolates of lyngbya majuscula collected from hector bay, jamaica, and boca del drago beach, bocas del toro, panama. the planar structure was deduced by one- and two-dimensional nmr spectroscopy. x-ray crystallography was used to determine the absolute stereochemistry of hectochlorin as 2s,3s,14s,22s. hectochlorin is equipotent to jasplakinolide (5) in its ability to promote actin polymerization, but unlike jasplakinolide, is unable to displace a fluoresc ...200212088429
3-farnesyl-2-hydroxybenzoic acid is a new anti-helicobacter pylori compound from piper multiplinervium.a new prenylated salicylic acid derivative, 3-farnesyl-2-hydroxy benzoic acid (1), was isolated from the leaves of piper multiplinervium c. dc. (piperaceae). it showed anti-helicobacter pylori activity (mic 37.5 microg/ml) and antimicrobial activity at mics between 2.5 and 5 microg/ml against staphylococcus aureus, escherichia coli, klebsiella pneumoniae, mycobacterium smegmatis, pseudomonas aeruginosa and candida albicans. its structure was elucidated by means of ms, 1h and 13c nmr. the ethnome ...200616266794
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