| genetic and phenotypic characterization of candida albicans strains isolated from infectious disease patients in shanghai. | candida albicans, as an opportunistic pathogen, can cause superficial and life-threatening candidiasis in immunocompromised individuals. the formation of surface-associated biofilms and the appearance of drug resistance pose a significant challenge for clinical intervention. in this study, a total of 104 hospital-acquired c. alibcans clinical isolates were collected from sterile sites and mucosal lesions of 92 infectious disease patients in the shanghai public health clinical center and analysed ... | 2015 | 25351710 |
| mechanisms of azole resistance in candida albicans clinical isolates from shanghai, china. | this study was undertaken to characterize the mechanism(s) of azole resistance in clinical isolates of candida albicans collected in shanghai, china, focusing on the role of efflux pumps, target enzymes of fluconazole (erg11), respiratory status and the ergosterol biosynthetic pathway. clinical isolates of c. albicans (n = 30) were collected from 30 different non-hiv-infected patients in four hospitals in shanghai. all 30 c. albicans isolates were susceptible to amphotericin b and 5-fluorocytosi ... | 2015 | 25748216 |
| multilocus sequence typing of pathogenic candida albicans isolates collected from a teaching hospital in shanghai, china: a molecular epidemiology study. | molecular typing of candida albicans is important for studying the population structure and epidemiology of this opportunistic yeast, such as population dynamics, nosocomial infections, multiple infections and microevolution. the genetic diversity of c. albicans has been rarely studied in china. in the present study, multilocus sequence typing (mlst) was used to characterize the genetic diversity and population structure of 62 c. albicans isolates collected from 40 patients from huashan hospital ... | 2015 | 25919124 |
| antifungal susceptibility and molecular typing of 115 candida albicans isolates obtained from vulvovaginal candidiasis patients in 3 shanghai maternity hospitals. | in our multicenter study, we studied the distribution of candida species in vulvovaginal candidiasis patients and investigated antifungal susceptibility profile and genotype of candida albicans in vaginal swab. a total of 115 candida albicans strains were detected in 135 clinical isolates. minimum inhibitory concentration determinations showed that 83% and 81% of the 115 candida albicans strains were susceptible to fluconazole and voriconazole. randomly amplified polymorphic dna analysis (rapd) ... | 2016 | 26468549 |
| molecular characterization of candida africana in genital specimens in shanghai, china. | candida africana, an emerging yeast pathogen, is closely related to candida albicans and most commonly involved in vulvovaginal candidiasis (vvc). however, its prevalence in candidal balanoposthitis is still unclear. in this study, the prevalence of c. africana in both candidal balanoposthitis and vvc in a sexually transmitted diseases (std) clinic in shanghai, china, was analyzed, and the molecular characterization and susceptible profiles of c. africana isolates were investigated. as results, ... | 2015 | 26665002 |
| [analysis on clinical and epidemioloical characteristics of measles in hospitalized children in shanghai in 2012]. | to investigate the main factors that influence measles morbidity and the genotype of measles virus, so as to provide evidence for scientific decision making to further control the prevalence of measles. | 2015 | 26717659 |
| otomycosis in shanghai: aetiology, clinical features and therapy. | otomycosis is frequently seen in shanghai and is a challenging problem due to recurrence and resistance to therapy. the aims of this study were to determine the pattern of fungal agents, sex distribution, clinical presentation, predisposing factors, complications and treatment outcomes of otomycosis. retrospective review of 108 patients with a clinical diagnosis of otomycosis treated from september 2009 to september 2010 in otolaryngology outpatient department. it has been found to be more preva ... | 2011 | 21999222 |