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[hiv patients with psychiatric illnesses. treatment strategies and drug interactions].since the beginning of the endemic phase of the human immunodeficiency virus (hiv), about 60,000 humans have been infected in germany by this retrovirus. epidemiological data indicate approximately 2,500 new infections annually. due to the multiagent antiviral therapy available, only about 600 cases progressed to the clinical picture of full-blown acquired immunodeficiency syndrome (aids) in 1999. [robert-koch-institut (berlin), http://www.rki.de] if an hiv infection or aids is current, a higher ...200111268765
phylogenetic analysis of acute hepatitis c virus genotype 4 infections among human immunodeficiency virus-positive men who have sex with men in germany.an ongoing hcv epidemic currently affects a growing proportion of hiv-positive men who have sex with men (msm) in europe. recently in the north-rhine region of germany, we have observed an increase in acute hcv infections of genotype 4 (hcv-4).201020633101
experiences of the dresdner cord blood bank, supported by the deutsche knochenmarkspenderdatei.allogeneic bone marrow and peripheral blood stem cell transplantation is the treatment of choice for some malignant hematologic diseases, marrow failure syndromes, and severe congenital immunodeficiency states. since gluckman et al reported in 1988 the first successful human leukocyte antigen (hla)-matched sibling umbilical cord blood stem cell transplantation, it has been known that cord blood is a valuable source of hematopoietic stem cells. the cord blood bank at the university hospital of dr ...199910632481
history of syringe sharing in prison and risk of hepatitis b virus, hepatitis c virus, and human immunodeficiency virus infection among injecting drug users in berlin.injecting drug users (idu) are at risk of parenterally transmitted diseases such as hepatitis b virus (hbv), hepatitis c virus (hcv), and human immunodeficiency virus (hiv) infection. we investigated whether a history of syringe sharing in prison is a risk factor for these infections. in the longitudinal part of the study, hbv, hcv, and hiv seroincidence rates were determined.19979447418
frontloading: a risk factor for hiv and hepatitis c virus infection among injecting drug users in berlin.to determine whether frontloading (i.e., syringe-mediated drug-sharing) is a risk factor for hiv, hepatitis b virus (hbv) and hepatitis c virus (hcv) infection among injecting drug users (idu).19968882671
frequency of genotypic and phenotypic drug-resistant hiv-1 among therapy-naive patients of the german seroconverter study.genotypic and phenotypic resistance of viral reverse transcriptase (rt) and protease (pr) was determined for 64 therapy-naive, hiv-1-infected seroconverters of the german seroconverter study coordinated by the robert koch-institut, berlin. the date of seroconversion of patients and the laboratory, clinical, and therapeutic follow-up data were documented. samples were collected between 1996 and 1999. phenotypic resistant hiv-1 were found in 8 (13%) seroconverters; in most cases resistance was wea ...200111242200
decline in the rate of oral opportunistic infections following introduction of highly active antiretroviral therapy.in recent years the management of human immunodeficiency virus (hiv)-positive individuals has been based on highly active antiretroviral therapy (haart) comprising a combination of nucleoside analogues or the combination of these agents with protease inhibitors. the aim of the present study was to describe the prevalence of oral lesions in a cohort of 103 hiv-seropositive patients on haart, to compare these data with the prevalence of lesions prior to haart and to correlate these finding with th ...200010947250
risk factors for hiv infection in german i.v. drug abusers. clinical, serological and epidemiological features.a series of 320 german i.v. drug abusers (32.2% female, 67.8% male) were tested in a cross-sectional study for antibodies against hiv. seroprevalence increased from 0 in those who discontinued i.v. drug abuse before 1982 to 37.2% in those who stopped injecting drugs in 1985/1986 or who were still addicted. antibodies to hiv were significantly associated with lymphadenopathy and clinical symptoms (fever, weight loss, diarrhea, fatigue, night sweat, dermal lesions) and with markers of hepatitis a ...19873495695
[the prevalence of human immunodeficiency virus (hiv) in blood donors in west germany and west berlin]. 19882462962
prevalence and determinants of anti-hcv seropositivity and of hcv genotype among intravenous drug users in berlin.a cross-sectional study was carried out to identify risk factors for seropositivity for antibodies against hepatitis c virus (hcv) and to assess to the distribution and determinants of hcv genotypes among intravenous drug users (ivdus). the study population consisted of 405 ivdus. serum specimens were tested for seromarkers for hcv, for human immunodeficiency virus (hiv), for hepatitis b virus (hbv) and for syphilis. hcv rna determination by polymerase chain reaction (pcr) and virus typing were ...19958658065
kaposi's sarcoma: a reevaluation.kaposi's sarcoma (ks) is a multicentric neoplasia of microvascular origin arising during development of immunodeficiency in human immunodeficiency virus (hiv)-infected individuals. more than 130 patients with hiv-associated ks (98% male homosexuals; median age, 35 years) have been diagnosed at the department of dermatology, university medical center steglitz, berlin, during the years 1982-1992. mucocutaneous and visceral involvement was a common finding in patients with hiv-associated ks, increa ...19957541146
time trends of hiv-i antibody prevalence in homosexual men.1840 homosexual and bisexual men were tested for human immunodeficiency virus type i (hiv) infection at the landesinstitut für tropenmedizin, berlin between april 1983 and december 1987. a total of 25.1% were seropositive for hiv, but the percentage was seemingly declining. during the study period we observed also a steady decrease in the prevalence of lymphadenopathy syndrome (las), antibodies to hepatitis b and syphilis, and high-risk sexual behaviour in the study population. by adjusting for ...19902331300
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