Publications

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use of lincomycin, methicillin and ristomycin in the nutrient media for isolating pathogenic intestinal microorganisms.elective-differentiating solid nutrient media for simultaneous isolation of vibrioes, salmonella and shigella were developed. antibiotics active against grampostive microflora and dry bile salts inhibiting the growth of proteus were used as the inhibitors of the growth of the accompanying microflora. the medium was lincomycin and the bile salts may be prepared in a dry form.19752096
[the epidemiology of cholera in derbent district, dagestan. the routes of the importation and spread of cholera].the epidemic of cholera in the derbent district of the daghestan was imported into the region. 172 cholera patients and 204 vibrio carriers were registered in 23 settlements of the region during the period of june 26 to october 12, 1994. the wide spread of this infection was facilitated by high migration activity of the population and the belated introduction of measures for limiting migration. the most severe outbreaks of cholera were observed in derbent and in the villages of mamedkala and mor ...19957771147
[cholera in makhachkala during the 1994 epidemic].during the period of epidemic in the daghestan 51 patients and 27 vibrio carriers were detected in makhachkala. a considerable proportion (30.7%) of cholera cases caused by infection imported from regions, unfavorable with respect to cholera, in the presence of pronounced migration of the population was registered. the role of different transmission routes in cases of cholera was as follows: day contacts were responsible for 43.3%, the alimentary route for 28.4% and the water route for 14.9% of ...19957771144
[cholera in a remote region of dagestan].the epidemic situation in a remote region of daghestan at the period of the cholera outbreak in the republic is considered with the use of concrete examples. the analysis of cases of cholera, as well as vibrio carriership, at the period of august 5 to october 5, 1994, is presented. the territorial and temporal separation of different cases of the disease and vibrio carriership were indicative of the periodic import of the causative agent to the territory of the town and the region from other pla ...19957771142
[the use of a cholera coagulating diagnostic agent under the cholera epidemic conditions in dagestan].dried cholera diagnosticum for the slide coagglutination test was obtained. the diagnosticum, found to be highly active and specific, permitted the detection of vibrio cholerae in the analyzed material at a concentration of 10(6)-10(8) microbial cells/ml. the diagnosticum was used during cholera epidemic in daghestan for the detection and rapid identification of cholera vibrios. in all cases the positive results of the coagglutination test were confirmed by other investigation methods (no cases ...19957771138
[a dna analysis of vibrio cholerae strains by the polymerase chain reaction].the method for the analysis of cholera toxin gene in v. cholerae strains was developed on the basis of polymerase chain reaction (pcr). this specific and highly sensitive method using primers affecting the site of the dna of the operon of cholera toxin gene made it possible to identify one copy of v. cholerae genome. for the first time the content of cholera toxin gene in 4 v. cholerae (eltor) strains, obtained from the clinical material of cholera patients in tajikistan and dagestan, was shown ...19969027173
[cases of intrahospital cholera infection]. 19957771162
[the properties of the vibrio cholerae strains isolated in large districts in western dagestan in 1994].190 v. cholerae cultures isolated by the specialized antiepidemic brigade of the rostov-on-don research institute for plague control in the khasavyurt, babayurt and novolaksk regions of daghestan in august-october 1994. all isolated strains were typical with respect to their morphological and cultural properties and could be agglutinated (with the exception of one strain) to the titer or half-titer with diagnostic cholera serum and ogawa serum. 4 strains had signs of ro-dissociation, 4 strains w ...19957771155
[the preservation of the causative agent of cholera in the water supplies of the central regions of dagestan (experimental data)].the acidic ph of water of surface water reservoirs in izberbash and two adjoining regions, including sea water, seems to be unfavorable for the prolonged preservation of vibrio cholerae eltor, but additional ecological investigations are necessary to study the possibility for infection to take root at this territory. water from the zam-zam spring, if contaminated with v. cholerae, may serve as a transmission factor, but the duration of its action is limited by the survival term of v. cholerae. t ...19957771154
[the bacteriophage lysis-susceptibility properties of vibrio cholerae strains isolated in separate regions of dagestan in 1994].the study of the properties of v. cholerae strains isolated in june-september 1994 in the daghestan revealed that they belonged, according to their specific properties, to typical representatives of v. eltor, serovar ogawa, but a great part of them (67.2%) was not lysed by diagnostic cholera bacteriophages. experiments with different batches of diagnostic cholera bacteriophages showed the necessity of their further improvement.19957771153
[the characteristics of vibrio cholerae isolated in dagestan in 1994].a high degree of resistance to cholera diagnostic phages and carriership of prophages characteristic of v. cholerae eltor strains vct+ were shown to be the specific features v. cholerae isolated in daghestan during the period of june-october 1994. among the strains under study, isolated respectively in 12 and 18 out of 19 regions of daghestan, a high proportion was found to have resistance to tetracycline (65%) and chloramphenicol (28.6%). moreover, some strains were found to be resistant to fur ...19957771152
[the characteristics of the antibacterial therapy for cholera in dagestan].wide circulation of antibiotic-resistant vibrio cholerae strains again gives prominence to the problem of etiotropic therapy. the results of the treatment of 428 persons infected with v.cholerae (237 cholera patients and 191 vibrio carriers) in different regions of daghestan during the outbreak of epidemic in 1994 are presented. the main criterion of the effectiveness of antibacterial therapy was the determination of the percentage of bacterial relapses. the sensitivity of 118 v.cholerae strains ...19957771151
[the cholera epidemic in mountainous regions of dagestan in relation to the probable role of the water factor in its spread].the follow-up of dynamics of cholera epidemic in 1994 was made in 4 mountain regions of daghestan with shared river system. there were 537 infection cases in these regions, which was equal to 1/4 from the total number of cholera patients in daghestan. the probability of cholera distribution by water way has been shown, which can be related to massive dissemination with v. cholerae in river, drink and waste water both from active, and from local (intrahospital) epidemic sources. vibrio's exit fro ...19957771149
[the epidemiology of cholera in derbent district. the characteristics of the epidemic process].cases of cholera in the derbent district of the daghestan took predominantly mild and moderate clinical forms. the ratio of patients to vibrio carriers was 1:1.25. the etiological agent of the epidemic was v. eltor, serovar ogawa. cholera patients were of greater epidemiological importance as the sources of infection in comparison with vibrio carriers. carrier state after convalescence was observed in 1.1% of cases. the population was infected with cholera, as a rule, through everyday contacts a ...19957771148
[cholera in the republic of dagestan].cases of cholera were registered in daghestan in all pandemics with the exception of the fourth one. for the first time the import this infection by pilgrims returning from their hajj by motor transport and traveling through the countries of southwest asia was registered. 184 settlements of 27 regions, 8 towns and 1 housing estate were involved in the epidemic process, the number of registered cholera cases and vibrio carriers being 2,327. high contamination rates were detected in regions situat ...19957771137
[an operative analysis of the cholera epidemic in the republic of dagestan using a computer database].the epidemiological information on cholera epidemic in daghestan during the period of june 6 to october 21, 1994, based on the data obtained from 2,327 patients and vibrio carriers in 184 settlements of 27 regions, 8 towns and 1 housing estate, was collected, systematized and analyzed with the use of the data base (db). the use of db made it possible to carry out the surveillance of the level of and dynamics of morbidity and infections rates, to determine the territories of risk, the age and soc ...19957771135
[the characteristics of the current stage in the development of the 7th cholera pandemic].the state and tendencies in the development of the epidemiological situation in cholera in the world (1961-1996) are evaluated. as revealed in this investigation, at the modern stage the development of the 7th pandemic characterized by the formation of stable and temporary endemic foci in a number of countries of asia, africa, central and south america and by the import of cholera from these foci to different countries of the world, including the cis countries and russia. the "trigger mechanism" ...19979460863
[microtest systems in the diagnosis of cholera].micro test systems for the biochemical identification of comma bacilli (mts-v) and for a rapid determination of their groups according heiberg (mts-h) were designed and commissioned into medical practice. the micro test systems showed their advantages before the control media of hiss and bacterium incubation media at studying the museum-kept and freely-obtained vibrio strains as well as at studying the concomitant microflora and clinical materials taken from ill people and vibrio-carriers during ...200312688218
[the routes of the spread of cholera in the shamil'skiĭ mountain district of dagestan].the routes of the spread of cholera were analyzed in 273 patients and vibrio carriers during the outbreak of cholera in a mountainous region of daghestan during the period of july 18 to september 4, 1994. cholera was found to spread mainly after funeral repasts and condolence visits accompanied by the dispensation of foodstuffs, transmission being realized through alimentary and contact routes. under the conditions of the absence of the centralized water supply system in mountain villages and th ...19957771145
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