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experience with the use of an investigational f(ab')2 heptavalent botulism immune globulin of equine origin during an outbreak of type e botulism in egypt.during an outbreak of type e foodborne botulism in cairo in 1991, an investigational equine f(ab')2 "despeciated" heptavalent botulism immune globulin (dbig) was provided to the egyptian ministry of health by the u.s. army. of 54 patients known to have been treated with antitoxins, 4 received commercially available trivalent antitoxins, 45 received dbig, and 5 received both commercial antitoxin and dbig. physicians recorded side effects in 10 (22%) of 45 patients who received dbig; in nine cases ...19968842274
a massive outbreak of type e botulism associated with traditional salted fish in cairo.in april 1991, 91 hospitalized patients in cairo were reported to the egyptian ministry of health with botulism intoxication. to define the spectrum of illness and identify a food vehicle, 45 patients were interviewed and a case-control investigation was conducted among families of 5 hospitalized patients. clinical specimens and specimens of implicated food were tested for toxin and cultured for clostridium botulinum. hospitalized patients had symptoms consistent with botulism; 18 (20%) of 91 re ...19938421179
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