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murray valley encephalitis acquired in western australia.to report a recent fatal case of encephalitis associated with evidence of murray valley encephalitis virus infection, only the second fatality from this infection in western australia.19911645843
seroepidemiology of arboviruses among seabirds and island residents of the great barrier reef and coral sea.duplicate neutralization tests were done on 401 avian and 101 human sera from island residents collected in the coral sea and on australia's great barrier reef against 19 known arboviruses. antibodies to a potentially harmful flavivirus, gadget's gully virus, were equally present (4%) in both avian and human sera. antibodies to another flavivirus, murray valley encephalitis, and an ungrouped isolate, csiro 1499, were also present in both populations with non-significantly different incidences. a ...19911657626
defined epitope blocking with murray valley encephalitis virus and monoclonal antibodies: laboratory and field studies.in an attempt to develop a specific serological test for murray valley encephalitis (mve) virus antibodies, a panel of mve monoclonal antibodies was utilised in defined-epitope blocking elisa tests. in sera of mice immunised singly and in combinations of mve, alfuy (alf), and kunjin (kun) viruses, blocking patterns usually distinguished mve infections from those of the other flaviviruses. when blocking tests with selected mabs were applied to 468 flavivirus antibody positive sera collected from ...19901700805
isolation of murray valley encephalitis and ross river viruses from aedes normanensis (diptera: culicidae) in western australia.of eight viruses isolated from 28,909 female (643 pools) aedes normanensis collected from the north of western australia, two were identified as murray valley encephalitis virus and six as ross river virus. the two isolates of murray valley encephalitis virus represent the first confirmed isolations of this virus from an aedes species. the possible implications of these findings with regard to virus survival mechanisms during the dry season are discussed.19892540334
kunjin virus isolates of australia are genetically homogeneous.the genomes of 22 isolates of kunjin virus (kun) from australia were characterized and compared using rnase t1 oligonucleotide fingerprinting. the results show that all isolates belonged to one topotype, the distribution of which covered the entire australian continent. this finding is similar to that of murray valley encephalitis virus, but in contrast to the results reported for some other flaviviruses such as saint louis encephalitis virus.19892552010
william c. reeves and arbovirus research in australia.william c. reeves was invited to australia in 1952 to take part in field studies of murray valley encephalitis. the results of his work led to various hypotheses which directed arbovirus research in australia for a generation. that and the people he influenced in australia made him a major figure in the development of australian arbovirus research.19872825554
the 5'-terminal non-coding region of murray valley encephalitis virus rna is highly conserved.the 5' non-coding region of the genomes of 11 isolates of murray valley encephalitis virus from australia and papua new guinea were examined by primer extension sequencing. although the 5' non-coding region of all isolates was found to be highly conserved, three isolates were significantly different in that they contained extra uridine residues. two of these isolates from papua new guinea contained an extra uridine residue, nominally positioned after nucleotide 54, which was absent from all but ...19902154536
genetic variation of murray valley encephalitis virus.the genomes of 21 isolates of murray valley encephalitis virus (mve) from australia and papua new guinea were characterized and compared using rnase t1 oligonucleotide fingerprinting. most australian isolates grouped in clusters that were linked with a similarity coefficient of greater than 75%, indicating substantial homogeneity. two isolates grouped as a cluster that linked with other isolates at a level of 67%. these two isolates, one from the north and one from the south-east of australia we ...19882841405
ord river arboviruses--serological epidemiology.this paper presents the results of haemagglutination-inhibition tests carried out on sera from 441 persons, 1,080 cattle and 335 birds in the kimberley area. two alphaviruses (group a) (ross river and sindbis) and one flavivirus (murray valley encephalitis) were used for the preparation of haemagglutinins in the haemagglutination-inhibition tests. the tests showed a high percentage of antibody of murray valley encephalitis in humans, birds and cattle, with an obvious focus of infection in the st ...19761021093
a method for predicting murray valley encephalitis in southeast australia using the southern oscillation.clinical cases of murray valley encephalitis in southeast australia have tended to occur in summer and autumn following extended periods of above average rainfall over most of eastern and northern australia. the southern oscillation, an important mode of climatic fluctuations over the indian and pacific oceans, is closely related to eastern and northern australian rainfall. the southern oscillation has been used previously to develop methods for predicting rainfall fluctuations over australia an ...19863036054
isolation of murray valley encephalitis virus and other arboviruses in the ord river valley 1972-1976.this paper summarizes the isolation of arboviruses from mosquitoes collected in the ord valley between 1972 and 1976. a total of one hundred and ninety five strains of at least fifteen antigenically distinct viruses have been isolated. seven of these isolates appear to be "new' antigenic types, and several are undergoing further testing. these are three new rhabdoviruses (kununurra [or194], a virus provisionally named kimberley [or250] and or189 [provisionally named parry's creek]), three ungrou ...19816117274
towards prediction and surveillance of murray valley encephalitis activity in australia.current practices for early warning of activity of murray valley encephalitis and other medically-important arboviruses are reviewed with view to improvement. data from previous papers on culex annulirostris populations, environmental factors and virus infection rates were reanalysed and the results considered as a basis for prediction and surveillance. this goal will only be achieved with improved national cooperation, a better epidemiological understanding and greater knowledge of the bionomic ...19806255919
transovarial transmission of murray valley encephalitis virus by aedes aegypti (l).in laboratory studies, murray valley encephalitis virus was transmitted transovarially by orally infected aedes aegypti to approximately 1.5% of both adult male and female progeny.19806263238
vector competence of culex pipiens quinquefasciatus for murray valley encephalitis, kunjin, and ross river viruses from australia.australian populations of culex pipiens quinquefasciatus say from brisbane, charleville, cairns, kowanyama (queensland), darwin (northern territory), mildura (victoria), and port hedland (western australia) proved to be either poorly susceptible or refractory to oral infection with low passage level murray valley encephalitis, kunjin, and ross river viruses. with respect to past or future epidemics of murray valley encephalitis or kunjin (both known to cause clinical encephalitis in man), and of ...19826285750
viruses recovered from mosquitoes and wildlife serum collected in the murray valley of south-eastern australia, february 1974, during an epidemic of encephalitis.pools of mosquitoes collected in the murray valley in february, 1974, during an encephalitis epidemic yielded 239 isolates of 11 distinct viruses. these included 39 isolates of mve virus, an incriminated causative agent of encephalitis in man, and 111 isolates of kunjin virus, a probable causative agent. an additional isolate of mve virus was recovered from the serum of a white-faced heron, ardea novaehollandiae. the other 9 viruses comprised the alpha-viruses ross river and sindbis, the flavivi ...19826299258
variation in arbovirus infection rates in species of birds sampled in a serological survey during an encephalitis epidemic in the murray valley of south-eastern australia, february 1974.there was extensive and exuberant breeding of waterbirds before and during an epidemic of arboviral encephalitis in the murray valley of south eastern australia in 1974. as estimated by haemagglutination inhibition tests on 432 bird sera collected between 4th and 13th february, 1974, infection with murray valley encephalitis virus, kunjin virus and possibly other flaviviruses was concentrated in species of the order ciconiiformes (55% positive) and pelecaniformes (41%), compared with only 5% in ...19826299259
australian encephalitis in western australia, 1978-1991.to review the various clinical manifestations of murray valley encephalitis (mve) or kunjin virus encephalitis in patients in western australia.19938386796
australian x disease, murray valley encephalitis and the french connection.epidemics of a severe encephalitis occurred in eastern australia between 1917 and 1925, in which over 280 cases were reported with a fatality rate of 68%. the disease had not been described previously and was called australian x disease. the next epidemic occurred in south-east australia in the summer of 1950-51. the disease was given its name of murray valley encephalitis as this was the area from which most cases were reported. a virus was isolated by eric french in victoria, and about the sam ...19958545982
the molecular epidemiology of kokobera virus.we describe herein the molecular epidemiology and phylogeny of kokobera (kok) virus, a flavivirus found in australia and papua new guinea. we sequenced a region encompassing the 200 nucleotides of the 3' terminus of the ns5 gene, and the first 300 nucleotides of the 3' untranslated region (utr). the study included 25 isolates of the virus, including an isolate from png, and several recent isolates from the south-west of western australia (wa), where the virus had not previously been detected. we ...200010930658
flaviviruses isolated from mosquitoes collected during the first recorded outbreak of japanese encephalitis virus on cape york peninsula, australia.in response to an outbreak of japanese encephalitis (je) virus on cape york peninsula, australia, in 1998, mosquitoes were collected using co2 and octenol-baited centers for disease control and prevention light traps. a total of 35,235 adult mosquitoes, comprising 31 species, were processed for virus isolation. no isolates of je virus were recovered from these mosquitoes. however, 18 isolates of kokobera virus, another flavivirus were obtained from culex annulirostris. twelve isolates were from ...200111442206
dengue and other emerging flaviviruses.flaviviruses are among the most important emerging viruses known to man. most are arboviruses (arthropod-borne) being transmitted by mosquitoes or ticks. they derived from a common ancestor 10-20000 years ago and are evolving rapidly to fill new ecological niches. many are spreading to new geographical areas and causing increased numbers of infections. traditionally, three clinical syndromes are recognized: fever-arthralgia-rash, viral haemorrhagic fever, and neurological disease, though for som ...200111531316
sentinel chicken surveillance programme in australia, 1 july 2001 to 30 june 2002.detection of flavivirus seroconversions in sentinel chicken flocks located throughout australia is used to provide an early warning of increased levels of murray valley encephalitis (mve) and kunjin virus activity in the region. during the 2001/2002 season low levels of flavivirus activity were detected in northern australia compared to previous years. mve and kunjin virus activity was detected in the kimberley and pilbara regions of western australia and the northern territory but not in north ...200212416705
clinical and laboratory findings on the first imported case of murray valley encephalitis in europe.murray valley encephalitis (mve) is an important mosquitoborne flavivirus infection endemic to australia and papua new guinea. we report the first imported case of mve in europe. a 23-year-old tourist developed severe encephalitis after having returned to germany from a long-term trip across the australian continent. the diagnosis was suspected on the basis of clinical findings and the patient's travel history and was confirmed by serological findings. the patient made a prolonged but complete r ...200312856229
epizootic activity of murray valley encephalitis and kunjin viruses in an aboriginal community in the southeast kimberley region of western australia: results of mosquito fauna and virus isolation studies.we undertook annual surveys of flavivirus activity in the community of billiluna in the southeast kimberley region of western australia between 1989 and 2001 [corrected]. culex annulirostris was the dominant mosquito species, particularly in years of above average rains and flooding. murray valley encephalitis (mve) virus was isolated in 8 of the 13 years of the study from seven mosquito species, but more than 90% of the isolates were from cx. annulirostris. the results suggest that mve virus is ...200314628944
flavivirus isolations from mosquitoes collected from western cape york peninsula, australia, 1999-2000.after the 1st appearance of japanese encephalitis virus (je) on mainland australia in 1998, a study was undertaken to investigate whether je had become established in enzootic transmission cycles on western cape york peninsula. adult mosquitoes were collected during the late wet season from kowanyama and pormpuraaw in april 1999, and pormpuraaw and barr's yard in april 2000. despite processing 269,270 mosquitoes for virus isolation, no isolates of je were obtained. however, other flaviviruses co ...200314710742
first record of aedes (aedimorphus) vexans vexans (meigen) in australia.aedes (aedimorphus) vexans vexans has become widely distributed in the australasian and oceanic islands zoogeographic regions, and in this paper, we describe the 1st confirmed report of ae. vexans vexans in australia. a total of 45 adult individuals were collected around the town of kununurra in the northeast kimberley region of western australia during the late wet seasons between 1996 and 2003. the majority (84%) was collected at trap sites in or near the ord stage i irrigation area. aedes vex ...200516033126
arboviral diseases and malaria in australia, 2007/08: annual report of the national arbovirus and malaria advisory committee.the national notifiable diseases surveillance system (nndss) received 8,671 notifications of diseases transmitted by mosquitoes in australia for the season 1 july 2007 to 30 june 2008. this represented a 39% increase from the annual average of 6,259 notifications for the previous 5 years. the alphaviruses, barmah forest and ross river, accounted for 7,760 (89%) of these notifications during the 2007/08 season and represents an increase when compared with the mean of the past 5 seasons. detection ...200919877534
application of satellite precipitation data to analyse and model arbovirus activity in the tropics.murray valley encephalitis virus (mvev) is a mosquito-borne flavivirus (flaviviridae: flavivirus) which is closely related to japanese encephalitis virus, west nile virus and st. louis encephalitis virus. mvev is enzootic in northern australia and papua new guinea and epizootic in other parts of australia. activity of mvev in western australia (wa) is monitored by detection of seroconversions in flocks of sentinel chickens at selected sample sites throughout wa. rainfall is a major environmental ...201121255449
sentinel chicken surveillance program in australia, july 2003 to june 2004.detection of flavivirus seroconversions in sentinel chicken flocks located in four australian states are used to provide an early warning of increased levels of murray valley encephalitis virus (mvev) and kunjin virus (kunv) activity in the region. during the 2003-2004 season low levels of flavivirus activity were detected in northern australia with both mvev and kunv virus activity detected in the kimberley and pilbara regions of western australia and in the northern territory. a single case of ...200515966677
flavivirus isolations from mosquitoes collected from saibai island in the torres strait, australia, during an incursion of japanese encephalitis virus.adult mosquitoes (diptera: culicidae) were collected in january and february 2000 from saibai island in the torres strait of northern australia, and processed for arbovirus isolation during a period of japanese encephalitis (je) virus activity on nearby badu island. a total of 84 210 mosquitoes were processed for virus isolation, yielding six flavivirus isolates. viruses obtained were single isolates of je and kokobera (kok) and four of kunjin (kun). all virus isolates were from members of the c ...200415347396
sentinel chicken surveillance program in australia, july 2002 to june 2003.detection of flavivirus seroconversions in sentinel chicken flocks located throughout australia is used to provide an early warning of increased levels of murray valley encephalitis (mve) and kunjin (kun) virus activity in the region. during the 2002-2003 season low levels of flavivirus activity were detected in northern australia compared to previous years. mve and kun virus activity was detected in the kimberley and pilbara regions of western australia and the northern territory but not in nor ...200314510063
epizootic activity of murray valley encephalitis virus in an aboriginal community in the southeast kimberley region of western australia: results of cross-sectional and longitudinal serologic studies.murray valley encephalitis (mve) virus is a mosquito-borne flavivirus causing severe encephalitis with a resultant high morbidity and mortality. in the period 1989-1993, we undertook a cross-sectional and longitudinal study by annually screening members of a small remote aboriginal community in northwestern australia for mve virus antibodies. of the estimated 250-300 people in the community, 249 were tested, and 52.6% had positive serology to mve. the proportion testing positive increased with i ...200212408675
reappearance of human cases due to murray valley encephalitis virus and kunjin virus in central australia after an absence of 26 years.murray valley encephalitis (mve) and kunjin virus disease are endemic in the tropical parts of the northern territory and western australia, but have been absent from central australia since 1974. in 2000, 5 laboratory-confirmed cases of encephalitis occurred over a short period in the normally dry inland region of central australia. the sudden occurrence of cases in march and april 2000 followed unusually high rainfall in the preceding months and evidence of flavivirus activity in the endemic a ...200211950201
kunjin virus: an australian variant of west nile?kunjin (kun) is a flavivirus in the japanese encephalitis antigenic complex that was first isolated from culex annulirostris mosquitoes captured in northern australia in 1960. it is the etiological agent of a human disease characterized by febrile illness with rash or mild encephalitis and, occasionally, of a neurological disease in horses. kun virus shares a similar epidemiology and ecology with the closely related murray valley encephalitis (mve) virus, the major causative agent of arboviral e ...200111797773
the relationships between west nile and kunjin viruses.until recently, west nile (wn) and kunjin (kun) viruses were classified as distinct types in the flavivirus genus. however, genetic and antigenic studies on isolates of these two viruses indicate that the relationship between them is more complex. to better define this relationship, we performed sequence analyses on 32 isolates of kun virus and 28 isolates of wn virus from different geographic areas, including a wn isolate from the recent outbreak in new york. sequence comparisons showed that th ...200111585535
early diagnosis of murray valley encephalitis by reverse transcriptase-polymerase chain reaction.a 4-year-old aboriginal boy developed encephalitis due to murray valley encephalitis virus (mve) following an earlier infection with kunjin virus (kun). the illness was severe, resulting in cerebral atrophy and profound physical and intellectual disability. the earlier kun infection complicated his serological profile and delayed antibody responses to mve. by contrast, the reverse transcriptase-polymerase chain reaction (rt-pcr) assay detected mve in serum 3 days after the onset of illness and 4 ...200010740807
a presumptive case of fatal murray valley encephalitis acquired in alice springs.a presumptive case of murray valley encephalitis (mve) acquired in alice springs in march 1997 is reported. the patient subsequently died in mackay. the diagnosis of murray valley encephalitis was supported by the detection of flavivirus igm in cerebrospinal fluid. low titres of igm specific to murray valley encephalitis and alfuy were detected in a single serum sample. the patient's travel movements indicate that his infection was acquired in the alice springs vicinity. this conclusion was furt ...19989648367
genetically determined resistance to flavivirus infection in wild mus musculus domesticus and other taxonomic groups in the genus mus.inherited resistance to flaviviruses in laboratory mice is a rare trait conferred by an autosomal dominant gene (flvr). to provide information on genetic resistance to flaviviruses in wild mice, we analysed (i) wild m. m. domesticus trapped in australia, and (ii) mice representing other species and subspecies in the genus mus. mice were screened for resistance relative to c3h/hej mice by intracerebral challenge with murray valley encephalitis virus or yellow fever virus, and breeding studies wer ...19989638142
arbovirus infections of humans in high-risk areas of south-eastern australia: a continuing study.to determine the current immune status of high-risk populations of new south wales and victoria to the arboviral pathogens, murray valley encephalitis (mve) and kunjin (kun) viruses, which are associated with australian encephalitis (ae), and ross river (rr) and kokobera (kok) viruses which are associated with polyarthritis. further, to estimate seroconversion rates to these viruses in high-risk populations over the 10-year period 1981-1991.19938393128
arboviruses causing human disease in the australasian zoogeographic region.over 65 arboviruses have been reported from countries in the australasian zoogeographic region, but only a few have been implicated in human disease. these include the flaviviruses murray valley encephalitis (mve), kunjin (kun), kokobera (kok), and dengue, particularly types 1 and 2; the alphaviruses ross river (rr), barmah forest (bf), and sindbis (sin); and the bunyaviruses, gan gan and trubanaman. in this paper recent epidemiological and clinical results pertaining to these viruses are review ...19948031248
immunodominant epitopes on the ns1 protein of mve and kun viruses serve as targets for a blocking elisa to detect virus-specific antibodies in sentinel animal serum.two mosquito-borne flaviviruses, murray valley encephalitis (mve) and kunjin (kun), are the aetiological agents of australian encephalitis. mve causes a severe and potentially fatal form of the disease while kun is responsible for only a few relatively mild cases. therefore it is important that serological tests used in flavivirus surveillance differentiate between infections with these two viruses. however, this has been hampered in the past by the close antigenic relationships between flavivir ...19957738140
serological evidence of inter-epidemic infection of feral pigs in new south wales with murray valley encephalitis virus.the sera of 617 feral pigs, collected from three widely separated areas of northern and central new south wales, were examined for antibody to murray valley encephalitis (mve) virus and to ross river virus. haemagglutination-inhibition (hi) antibody was detected to mve in 58% of sera and to ross river virus in 15% of sera. neutralization tests suggested that the mve hi antibody resulted from infection with mve virus in the summers of 1971-1972 and 1972-1973 when the virus was not known to be act ...19761016127
murray valley encephalitis virus field strains from australia and papua new guinea: studies on the sequence of the major envelope protein gene and virulence for mice.we have compared the nucleotide sequence of the gene encoding the major envelope (e) protein of a number of murray valley encephalitis virus (mve) isolates from australia and papua new guinea (png). the isolates, from widely separated geographic regions, were from four fatal human cases, a heron, and six mosquito pools and covered a period of 25 years. the sequences of the australian strains were notable for their similarity, showing not more than 1.7% nucleotide sequence divergence in pairwise ...19882838962
experimental infection with murray valley encephalitis virus. pigs, cattle, sheep, dogs, rabbits, macropods and chickens.a total of 142 young animals including 10 domestic and 14 feral pigs, 12 hereford calves, 12 crossbred and 24 merino lambs, 11 dogs, 8 domestic and 16 feral rabbits, 14 grey kangaroos, 9 agile wallabies and 12 chickens was exposed to infection with 4 strains of murray valley encephalitis virus (mve), mainly using orally infected culex annulirostris mosquitoes. in terms of their viraemic response, the animals were grouped into high (grey kangaroos, rabbits), moderate (pigs, dogs, chickens) and lo ...19852990398
effect on mice of infection during pregnancy with three australian arboviruses.infection of pregnant mice with ross river or getah viruses after the establishment of a functional placenta resulted in fetal infection with these viruses. however, only with ross river virus was there any significant fetal death. there was significant post-partum mortality in mice infected in utero with ross river but not with getah virus. in contrast, significant post-partum mortality occurred in murray valley encephalitis virus-infected mice despite the inability of the virus to cross the pl ...19816259957
arbovirus infection in a murray valley community.serum antibodies to ross river virus and murray valley encephalitis virus were measured during 1974-1975 in residents of echuca, an urban murray valley community. a representative group of volunteers was obtained by random selection of households. the prevalence of antibodies to both viruses increased progressively with age. prevalence was equal in both sexes for both viruses in all age groups, indicating that the risk of infection was mainly determined by geography rather than by personal activ ...19863010928
arbovirus infections of humans in new south wales. seroepidemiology of the flavivirus group of togaviruses.a seroepidemiological study of 16 842 human sera, collected in 1981 and 1982 from all health regions of new south wales, was carried out using the haemagglutination-inhibition (hi) test and eight australasian flaviviruses: murray valley encephalitis (mve); kunjin (kun); alfuy (alf); stratford (str); kokobera (kok); edge hill (eh); sepik (sep); and saumarez reef (sre). a limited survey was also carried out with two recently discovered flaviviruses, gadgets gully and csiro 946. antibody prevalence ...19853007952
genetic differentiation of murray valley encephalitis virus in australia and papua new guinea.the genetic relatedness of ten murray valley encephalitis virus (mve) isolates from australia has been examined by comparing haeiii and taqi restriction digest profiles of cdna to virion rna. the isolates were from the murray valley region of south-eastern australia and from the ord river region of western australia and spanned a period of 23 years (1951-1974). the isolates generated closely similar restriction digest profiles. the extent of similarity suggested that the level of nucleotide sequ ...19862884985
the viruses of australia and the risk to tourists.australia is a climatically diverse country varying from a tropical climate in the north to arid central desert and grassland regions, and to temperate climates in the south. there are many viral infections found in australia that are common to developed countries worldwide, but this article will focus on those that pose a special risk for travellers to australia, especially the mosquito-borne viruses. the commonest are the members of the alphavirus genus, particularly ross river virus and barma ...201121679887
arboviral diseases and malaria in australia, 2008-09: annual report of the national arbovirus and malaria advisory committee.the national notifiable diseases surveillance system received 8,677 notifications of diseases transmitted by mosquitoes in australia from 1 july 2008 to 30 june 2009. the alphaviruses, barmah forest and ross river, accounted for 6,574 (78%) of these notifications during 2008-09. there were 1,009 notifications of dengue virus infection locally-acquired in north queensland and 484 notified cases resulted from overseas travel. notification rates of dengue virus infection for 2008-09, regardless of ...201021090179
communicable diseases network australia national arbovirus and malaria advisory committee annual report, 2006-07.this report describes the epidemiology of mosquito-borne disease in australia for the mosquito-borne disease season 1 july 2006 to 30 june 2007, which was moderately low compared to previous seasons. ross river virus (rrv) infections (55%), barmah forest virus (bfv) infections (29%) and overseas acquired malaria (11%) were the most common mosquito-borne diseases reported in 2006-07. the number, proportion and rate of national bfv notifications were the second highest on record since 1998-99. the ...200818522303
genetic and phenotypic differences between isolates of murray valley encephalitis virus in western australia, 1972-2003.murray valley encephalitis virus (mvev) is a medically important mosquito-borne flavivirus found in australia and papua new guinea (png). partial envelope gene nucleotide sequences of 28 isolates of mvev from western australia (wa) between 1972 and 2003 were aligned and compared phylogenetically with the prototype mve-1-51 from victoria in 1951 and isolates from northern queensland and png. monoclonal antibody-binding patterns were also investigated. results showed that the majority of isolates ...200717393295
short report: the first isolation of japanese encephalitis virus from mosquitoes collected from mainland australia.in response to an incursion of japanese encephalitis virus (jev) on cape york peninsula, australia, in 2005, 23,144 culex mosquitoes were processed for virus detection. a single isolate of jev was obtained from a pool of culex sitiens subgroup mosquitoes. this is the first reported mosquito isolate of jev from the australian mainland.200616837702
identification of new flaviviruses in the kokobera virus complex.novel flavivirus isolates from mosquitoes collected in northern australia were analysed by partial genomic sequencing, monoclonal antibody-binding assays and polyclonal cross-neutralization tests. two isolates were found to be antigenically distinct from, but related to, viruses of the kokobera virus complex, which currently contains kokobera (kokv) and stratford (strv) viruses. nucleotide sequence comparison of two separate regions of the genome revealed that an isolate from saibai island in th ...200515604438
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