Publications

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childhood diarrhoea in a low-income urban community in bangkok: incidence, clinical features, and child caretaker's behaviours.a one-year surveillance study of childhood diarrhoea in a low-income urban community in bangkok revealed an annual incidence of 2.2 episodes per child among infants, and that the overall annual incidence among children under five years of age was 0.9 per child. rotavirus, salmonella and campylobacter jejuni were common aetiologic agents. in children less than one year, diarrhoea was caused mostly by rotavirus and salmonella. in 1-2 year old children, the major causative agent was rotavirus while ...19911787280
epidemiologic aspects of shigellosis and other causes of dysentery in thailand.nearly 20% of children seen in the outpatient department of children's hospital in bangkok, thailand, for diarrheal disease had bloody diarrhea. shigella species and enteroinvasive escherichia coli--isolated from 13% and 2% of children with diarrhea, respectively--were the most frequent causes of bloody diarrhea. campylobacter species and nontyphoidal salmonella species were also isolated frequently but were much less often associated with bloody diarrhea. shigella species were rarely isolated f ...19912047642
importance of salmonellae and campylobacter jejuni in the etiology of diarrheal disease among children less than 5 years of age in a community in bangkok, thailand.the etiology of diarrhea in children less than 5 years of age in a low-income housing project in bangkok, thailand, was determined over 1 year. nontyphoidal salmonellae (13%), campylobacter jejuni (12%), rotavirus (12%), enterotoxigenic escherichia coli (7%), shigellae (6%), e. coli that hybridized with the enteropathogenic e. coli adherence factor probe (3%), and enteroinvasive e. coli (1%) were identified in 345 episodes of diarrhea in children less than 5 years of age. salmonellae were identi ...19902254427
seroprevalence of helicobacter pylori infections in thailand.serologic studies in developed countries indicate that helicobacter (formerly campylobacter) pylori infection is uncommon until the third decade of life and achieves a peak prevalence of 50% in the seventh decade. in developing countries the epidemiology of h. pylori has not well been described. a sensitive and specific serologic assay for h. pylori infection was validated in thai patients also studied by culture and histologic examination of biopsy specimens. the prevalence of h. pylori antibod ...19902345304
[antibiotic resistance and distribution of plasmid-encoded beta- lactamases among agents of traveller's diarrhea].the polymicrobial aetiology of travellers's diarrhoea in 356 tourists travelling in thailand and burma was investigated. besides enterotoxigenic e. coli, salmonella sp. and campylobacter fetus ssp. jejuni were identified as the most important enteric pathogens. minimal inhibitory concentrations of several commonly used antibiotics were determined to reveal the percentage of enteric pathogens being resistant. 36.2% e. coli strains were found to be resistant to ampicillin and 14.3% of the campylob ...19862943094
erythromycin-resistant campylobacter infections in thailand.erythromycin therapy was compared with no treatment in a prospective trial of acute diarrheal disease among 100 infants in an orphanage in bangkok. within 24 h of the onset of diarrhea, 50 children received erythromycin ethylsuccinate (40 mg/kg per day) in four divided doses for 5 days. campylobacter jejuni isolated from 31, campylobacter coli isolated from 21, and shigella spp. isolated from 21 of 100 children were the most commonly recognized pathogens; use of a sensitive, nonselective method ...19873579261
viruses and bacteria in pediatric diarrhea in thailand: a study of multiple antibiotic-resistant enteric pathogens.children with diarrhea admitted to a rehydration ward of a children's hospital in bangkok were investigated to determine the prevalence of enteric pathogens, the extent of children's previous antibiotic therapy, and the frequency of plasmid-mediated antibiotic resistance among infecting bacteria. rotavirus (36%), enterotoxigenic escherichia coli (18%), shigella (9%), salmonella (6%), campylobacter jejuni/coli (4%), and vibrio cholerae (2%) infections were among 105 children with diarrhea. antibi ...19816275727
a longitudinal study of the prevalence of bacterial enteric pathogens among adults with diarrhea in bangkok, thailand.six hundred sixty adults with diarrhea treated at bamrasnaradura hospital, bangkok, thailand were investigated to determine the prevalence, seasonality, and severity of diarrhea associated with bacterial enteric pathogens in 1980 and 1981. shigella were isolated from 27% and vibrio parahaemolyticus from 19% of the patients studied. enterotoxigenic escherichia coli (5%), salmonella (3%), non-01 vibrio cholerae (3%), campylobacter jejuni (1%), and group f vibrio (less than 1%) were isolated from a ...19836370564
protozoan enteric infection in aids related diarrhea in thailand.the aim of this study was to determine the prevalence of enteric protozoa and other pathogens in aids patients with diarrhea in bangkok, thailand. of 288 consecutive patients screened in the 10 month period between november 1999-august 2000 inclusive, 55 (19.2%) had cryptosporidium spp, 13 (4.5%) had isospora oocyst, 11 (3.8%) had giardia lamblia, 3 (0.9%) had entamoeba histolytica, and 1 (0.3%) had iodamoeba butschlii infection. the prevalence of microsporidia was 11% in this study. of 251 pati ...200112041580
emerging fluoroquinolone and macrolide resistance of campylobacter jejuni and campylobacter coli isolates and their serotypes in thai children from 1991 to 2000.this study investigated fluoroquinolone, macrolide resistances and serotype distributions among campylobacter jejuni and campylobacter coli isolated from children in bangkok and rural settings during 1991-2000. phenotypic identification, serotyping, and susceptibility testing were performed by standard microbiological procedures. the predominant serotypes of c. jejuni were lior 36, 2 and 4 and of c. coli were lior 8, 29 and 55. resistance to nalidixic acid increased significantly during 1991-200 ...200717306054
prevalence of foodborne microorganisms in retail foods in thailand.worldwide, foodborne illness is often associated with consumption of meats and poultry products sold at retail markets. a cross-sectional retail food study was conducted in bangkok, thailand to assess the prevalence of bacterial pathogens on retail food samples. raw chicken, beef, pork, and chicken eggs were purchased from fresh markets and supermarkets and tested for salmonella spp., campylobacter spp., arcobacter spp., and enterococcus spp. suspect bacterial pathogens were isolated by differen ...200717600488
diarrhea among children admitted to a private tertiary-care hospital, bangkok, thailand: a case series.we report here a case series of pediatric diarrhea cases admitted to a private tertiary-care hospital in bangkok, thailand. retrospective data were collected from computerized medical records of 2,001 children with diarrhea (80.9% thai), ages birth to 14 years, admitted to our facility during 2000-2005. the most common symptom leading to admission was vomiting (34.6%), while the most common sign was dehydration (63.6%). the largest proportion was comprised of toddlers (45.4%), followed by infant ...200818564682
bacterial enteric pathogens in children with acute dysentery in thailand: increasing importance of quinolone-resistant campylobacter.current data on pathogen prevalence and drug resistance patterns are important for treatment and vaccine-development strategies. an etiologic study of acute bacterial dysentery was conducted in children up to 12 years of age in 2 major hospitals in and around bangkok. stool samples or rectal swabs and clinical data were collected. standard microbiological methods were used to detect salmonella, shigella, campylobacter, vibrio, aeromonas and plesiomonas. pathogenic e. coli (etec, eiec, stec) was ...200212757222
foods as a source of enteropathogens causing childhood diarrhea in thailand.foods obtained in markets in bangkok were cultured for bacterial enteric pathogens and examined for their similarity to strains isolated from children under 5 years of age in bangkok in 1986. salmonella was isolated from 17%, campylobacter from 12%, and enterotoxigenic escherichia coli (etec) from 3% of 510 foods examined. campylobacter was isolated from 13.5%, etec from 13%, and salmonella from 12% of 1,230 children under 5 years of age with diarrhea. eighty-eight percent of children infected w ...19883041859
isolation of campylobacters from the canals of bangkok metropolitan area.the 100 ml of canal water samples of 36 canals in bangkok metropolitan area were examined in three periods starting from july-september 1988, november 1988-january 1989 and february-april 1989. each time the 52 water samples were checked. of 156 water samples, 116 strains of campylobacter species were isolated. they were 63.79 per cent (74 strains) of c. cryaerophila and 36.21 per cent (42 strains) of c. cryaerophila-like organisms. the differentiation was determined by urease activity test. c. ...19921487683
enteric pathogen sampling of tourist restaurants in bangkok, thailand.travelers' diarrhea (td) is the most prevalent disorder affecting travelers to developing countries. thailand is considered "moderately risky" for td acquisition, but the risk by city visited or behavior of the visitor has yet to be definitely defined. restaurant eating is consistently associated with the acquisition of diarrhea while traveling, and pathogen-free meals serve as a marker of public health success. this study seeks to ascertain a traveler's risk of exposure to certain bacterial gas ...201020412179
antimicrobial resistance of campylobacter species isolated from edible bivalve molluscs purchased from bangkok markets, thailand.campylobacter species have been recognized as the most commonly reported cause of bacterial gastroenteritis in humans. the increase of resistance rates to drugs of choice used for treatment in campylobacteriosis is becoming a public health concern. in parallel, the increased use of antimicrobials in aquaculture may lead to the emergence of resistant microorganisms and is likely to cause additional health risk to humans through food consumption. the study assesses the presence of antimicrobial re ...200919622033
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