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sinonasal and sino-orbital aspergillosis in 23 cats: aetiology, clinicopathological features and treatment outcomes.aetiology, clinicopathological findings and treatment outcomes were documented in 23 cats (1.5-13years of age) with sinonasal (sna, n=6) or sino-orbital (soa, n=17) aspergillosis. cases recruited retrospectively and prospectively were included if fungal hyphae were identified on cytological or histological examination and the fungal pathogen was identified by pcr and dna sequencing (its1 or its1-5.8s-its2 regions, rdna gene cluster). fungal culture was positive in 22/23 cases. in cases of sna, t ...201121388842
clinical associations and prevalence of scedosporium spp. in australian cystic fibrosis patients: identification of novel risk factors?risk factors for the association of scedosporium in cases of cystic fibrosis (cf) and its clinical implications are poorly understood. clinical, lung function and laboratory data of adult cf patients in sydney (april 2008-march 2009) were prospectively analysed for such risk factors. expectorated sputa were cultured for bacteria and examined for fungi using standard mycological and scedosporium-selective media, and by an internal transcribed spacer region-targeted multiplex pcr assay. scedospori ...201021067328
clinical profile of adult cystic fibrosis patients with frequent epidemic clones of pseudomonas aeruginosa.earlier reports suggested that pseudomonas aeruginosa frequent epidemic clones circulating in cystic fibrosis (cf) centres had increased virulence. however, recent data show no consistent associations with virulence, and suggest attenuation of virulence in chronic infection. changes to infection control programmes in relation to frequent epidemic clones should be based on their frequency, virulence across all age groups and mode of acquisition. the australian epidemic strain-1 (aes-1) (or the me ...201020573059
prevalence of allergic bronchopulmonary aspergillosis in cystic fibrosis in an area with a high frequency of atopy.lower airway colonisation with aspergillus fumigatus and the complicating hypersensitivity reaction allergic bronchopulmonary aspergillosis (abpa) is well recognised in patients with cystic fibrosis (cf). there is a wide range in reported prevalence of abpa in cf. differences in predisposing factors such as atopy and climatic humidity, but also differences in reporting may in part explain this observation. in the australian population there is a high frequency of atopy and the climate is relativ ...200515939251
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