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a typhus-like illness caused by acute hiv seroconversion.a patient is described in whom an acute human immunodeficiency virus seroconversion illness occurred following a trip to southern africa. the presentation was strikingly similar to that of african tick typhus and could only be distinguished by serological testing.19911905405
serological screening tests for syphilis in pregnancy: results of a five year study (1983-87) in the oxford region.between 1983 and 1987, 62 out of 76519 pregnancies in 51 mothers had a positive miniaturised treponema pallidum haemagglutination assay (tpha) test--1 in 1234, or 0.81 per 1000 births. about two thirds of these mothers had syphilis and the remainder non-venereal treponematoses such as yaws or pinta. antenatal screening identified 13 patients with previously unknown acquired syphilis, 11 of whom were given antibiotics during pregnancy. there were six fetal losses among the 62 tpha positive pregna ...19892515214
isolation and characterisation of intestinal spirochaetes.faeces or rectal swabs from 1527 subjects were examined for the presence of intestinal spirochaetes by anaerobic culture on blood agar incorporating spectinomycin (400 mg/l). twenty three specimens (1.5%) were positive, and only one of these came from a patient with diarrhoea. all positive specimens came from either asians or known homosexuals. comparative tests showed a close phenotypic similarity between the human isolates and non-pathogenic porcine intestinal spirochaetes. these organisms dif ...19863722407
results of serological tests for syphilis among gurkhas and other high risk groups.serological tests for syphilis gave more positive results in serving gurkha (nepali) soldiers from west nepal than in those from east nepal or in gurkha recruits. the soldiers had served from four to 11 years. the source of their infection was not clear. positive results were rather less common in black patients born in the tropics attending a genitourinary medicine in london and were similar to findings in blood donors in the west indies. british born male patients attending a genitourinary med ...19853910540
treponema pallidum haemagglutination assay in the routine serodiagnosis of treponemal disease. 19734583971
changing patterns of treponemal disease. 19744603001
serological tests for syphilis. 19725083447
assessment of the "luotest" in late syphillis. 19665947598
infectious and active yaws in a midland city. 19676028711
investigation into the spread of swine dysentery in 25 herds of east anglia and assessment of its economic significance in five herds.of 25 outbreaks of swine dysentery investigated, 22 were considered to have resulted from the purchase of pigs from farms known to be infected, two from the introduction of treponema hyodysenteriae on the boots of the stockman, and one from the accidental entry of infected pigs into a 'closed' herd. the hidden costs of swine dysentery in terms of an increased food conversion ratio may be more than four times the cost of medication. a method of halting the spread of disease is described.19817324356
evidence for lyme disease in urban park workers: a potential new health hazard for city inhabitants.in the uk, cases of lyme disease have only been reported from rural areas. recently, however, ixodes ticks infected with borrelia burgdorferi have been found in london parks. to determine whether this constituted a health hazard, we questioned 44 workers from richmond and bushey parks to assess their exposure to tick bites and whether they had a clinical history of lyme disease. their serum was subsequently investigated for antibodies to two different preparations of borrelia burgdorferi (whole ...19948162475
periodontopathic bacteria in english hiv-seropositive persons.selected periodontopathic bacteria were sought in 20 hiv-infected english patients and eight noninfected control subjects with similar periodontal status, using highly specific dna probes. actinobacillus actinomycetemcomitans (a. a), porphyromonas gingivalis, campylobacter rectus, prevotella intermedia, and fusobacterium nucleatum were more frequently detected and were found at higher levels in hiv-infected individuals than in controls. significantly increased levels of treponema denticola but, ...199910842858
primary syphilis remains a cause of oral ulceration.after many years the incidence of infective syphilis (infection with treponema pallidum) is increasing in the united kingdom. this may reflect changes in sexual attitudes and behaviour, altering trends in hiv disease, and increased foreign travel. oral disease as a consequence of primary syphilis is rare. the present report details two patients presenting to an oral medicine clinic in london, within a 6-month period in 1999, with oral ulceration as their only clinical manifestation of undiagnose ...200011081944
use of pcr in the diagnosis of early syphilis in the united kingdom.to evaluate a treponema pallidum polymerase chain reaction (pcr) test in the laboratory diagnosis of early syphilis in the united kingdom. subjects and setting: men and women attending genitourinary medicine clinics in england.200314663125
bovine digital dermatitis and severe virulent ovine foot rot: a common spirochaetal pathogenesis.a potential pathological role for spirochaetes in bovine digital dermatitis (bovine dd) and severe virulent ovine foot rot (svofr) has been considered and a treponeme isolate obtained from each disease in the uk. in this work, we have investigated the hypothesis that the two diseases may have a shared (common) spirochaetal aetiology. experiments were designed to identify serological similarities and differences between the two spirochaetes; an enzyme-linked immunosorbent assay (elisa) was develo ...200515727915
detection and follow up of infants at risk of congenital syphilis. 200616790724
audit of laboratory diagnostic methods for syphilis in england and wales.the number of cases of infectious syphilis is increasing rapidly across england and wales. concern has been expressed about diagnostic delay and its potential impact on patient care. a standard operating procedure for the serological diagnosis of syphilis has recently been developed by the health protection agency. this study aimed to audit clinical and laboratory practice in england and wales against this standard.200919004864
risk of sexually transmitted infections and violence among indoor-working female sex workers in london: the effect of migration from eastern europe.objectives to examine risk factors associated with hiv and sexually transmitted infections (stis) and experience of physical and sexual violence among sex workers in london, with a particular focus on differences in risk between migrants from eastern europe (ee) or the former soviet union (fsu) and uk-born sex workers. methods the authors conducted a cross-sectional survey of sex workers born in the uk, ee or fsu (n=268), collecting behavioural data, testing for antibodies to hiv and treponema p ...201121572111
high prevalence of macrolide resistant treponema pallidum strains in a london centre.macrolide resistant treponema pallidum strains, caused by mutations in the 23s ribosomal rna (23s rrna) gene, are widespread and increasingly prevalent. the authors aimed to establish the strain types of t pallidum isolated from patients in a london sexual health centre and to determine the frequency of macrolide resistance.201121917695
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