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orf virus infection in humans--new york, illinois, california, and tennessee, 2004-2005.orf virus is a zoonotic parapoxvirus endemic to most countries in the world and is principally associated with small ruminants (e.g., sheep and goats). human orf infections appear as ulcerative skin lesions after contact with an infected animal or contaminated fomite. this report summarizes the epidemiologic and laboratory investigations of four sporadic cases of human orf infection, emphasizing the temporal association between human lesions and skin trauma or recent flock vaccination with live ...200616437055
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