| ten year follow-up study of women presenting to a genitourinary medicine clinic with anogenital warts. | one hundred heterosexual women presenting at our clinic in 1979 with anogenital warts, were reviewed 10 years later. median duration of warts following initial clinic attendance was 2 months (range 0-120 months). in 1979 cervical pap smear results were available for 76 patients; cervical intraepithelial neoplasia (cin) was seen in 15/76 (19.7%) women; 3 (4%) women had low grade cin, 12 (15.7%) women had high grade cin. nineteen women had had treatment for cin between 1979 and 1989, 7 laser ablat ... | 1992 | 1543764 |
| a study of hpv 1, 2 and 4 antibody prevalence in patients presenting for treatment with cutaneous warts to general practitioners in n. ireland. | three hundred and seventy-six patients attending their general practitioner with cutaneous warts at five health centres in northern ireland were screened for human papilloma virus (hpv) types 1 and 2 igm antibody using an indirect immunofluorescence test. eight-eight (23.4%) patients were positive for hpv type 1 igm and 156 (41.5%) for hpv type 2 igm. hpv 1 igm antibody was significantly more likely to be associated with plantar warts than warts elsewhere (p less than 0.0001). hpv 2 igm was pres ... | 1988 | 2850937 |
| hpv prevalence and type-distribution in cervical cancer and premalignant lesions of the cervix: a population-based study from northern ireland. | assessment of human papillomavirus (hpv) prevalence and genotype distribution is important for monitoring the impact of prophylactic hpv vaccination. this study aimed to demonstrate the hpv genotypes predominating in pre-malignant and cervical cancers in northern ireland (ni) before the vaccination campaign has effect. formalin fixed paraffin embedded tissue blocks from 2,303 women aged 16-93 years throughout ni were collated between april 2011 and february 2013. hpv dna was amplified by pcr and ... | 2016 | 26680281 |
| does cervical screening in young women aged 20-25 years lead to unnecessary and harmful interventions? | cervical human papillomavirus (hpv) infection among young women (20-25 years of age) is common and normally transient. there are growing concerns that referral to a colposcopy clinic may lead to unnecessary treatment with an increased risk of obstetric complications. therefore, the purpose of this study was to determine the level of intervention for cervical abnormalities in this age group of the northern ireland population. | 2015 | 26434874 |
| the costs of managing genital warts in the uk by devolved nation: england, scotland, wales and northern ireland. | genital warts, 90% of which are caused by human papillomavirus types 6 and 11, are a significant problem in the uk. the cost of managing genital warts was previously estimated at £52.4 million for 2010. the objective of this study was to estimate the cost of genital warts management up to 2012 in the uk and by jurisdiction. population statistics and the number of reported genital warts cases in genito-urinary medicine clinics were obtained and extrapolated to 2012. cases of genital warts treated ... | 2016 | 25681263 |
| prevalence of human papillomavirus in women attending cervical screening in the uk and ireland: new data from northern ireland and a systematic review and meta-analysis. | there is substantial international variation in human papillomavirus (hpv) prevalence; this study details the first report from northern ireland and additionally provides a systematic review and meta-analysis pooling the prevalence of high-risk (hr-hpv) subtypes among women with normal cytology in the uk and ireland. between february and december 2009, routine liquid based cytology (lbc) samples were collected for hpv detection (roche cobas® 4800 [pcr]) among unselected women attending for cervi ... | 2013 | 23161367 |
| hpv16 and hpv18 genotyping triage in young women with borderline cytology or mild dyskaryosis: effect of age on genotype-specific risk of high-grade cin. | human papillomavirus (hpv) triage of borderline cytology or mild dyskaryosis is limited by the higher prevalence of hpv in women with these findings relative to those with high-grade cervical intraepithelial neoplasia (≥cin2). this is particularly relevant in young women in whom hpv prevalence is discernible. in a previous analysis of hpv triage and colposcopy outcomes in northern ireland, we revealed a substantial amount of prevalent high-grade disease in women below 30 years of age. we explore ... | 2016 | 26873051 |